PET-MR measurement with a norepinephrine transporter (NET)-selective radiotracer (S,S)-[11C]Omethylreboxetine ([11C]MRB) for Alzheimer's Disease
This trial aims to test whether abnormalities in the locus coeruleus, a brainstem region, can be measured in people with preclinical Alzheimer's disease and whether these abnormalities affect sleep and attention.
8 Primary · 1 Secondary · Reporting Duration: Visit 4 (1-4 weeks after LP)
Side Effects for
1 Treatment Group
Cognitively Normal (CN) Older Adults
1 of 1
30 Total Participants · 1 Treatment Group
Primary Treatment: PET-MR measurement with a norepinephrine transporter (NET)-selective radiotracer (S,S)-[11C]Omethylreboxetine ([11C]MRB) · No Placebo Group · N/A
Who is running the clinical trial?
Age 60 - 75 · All Participants · 6 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Is the eligibility criteria for this trial restricted to adults aged 18 and above?
"As stated in the terms of inclusion, those hoping to partake must be between 60 and 75 years old." - Anonymous Online Contributor
Are there any vacant spots remaining in this research project?
"Clinicaltrials.gov reveals that this clinical trial is open to applicants; the research was initially announced on August 6th 2020, and has been modified most recently October 19th 2022." - Anonymous Online Contributor
How many participants are currently being enrolled in this clinical research?
"Affirmative. The publically available details on clinicaltrials.gov display that this research is open to participants, after being initially posted on August 6th 2020 and last amended on October 19th 2022. Currently, 30 volunteers are needed from two different medical facilities." - Anonymous Online Contributor
Do the requirements for this research trial align with my qualifications?
"To qualify for this research project, applicants must have a diagnosis of Alzheimer's Disease and be within the range of 60 to 75 years old. The clinical trial is currently seeking thirty participants." - Anonymous Online Contributor