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Non-invasive Brain Stimulation

Theta Burst Stimulation for Alzheimer's Disease

N/A
Waitlist Available
Led By Michael H Rosenbloom, MD
Research Sponsored by HealthPartners Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 9 weeks
Awards & highlights

Study Summary

This trial will use brain scans to find areas of the brain that are not functioning properly in people with Alzheimer's disease. These areas will then be targeted with transcranial magnetic stimulation in an effort to improve brain function and slow the progression of Alzheimer's disease.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~9 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 9 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in connectivity measure of the TGd parcellations.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Intermittent theta burst stimulationExperimental Treatment1 Intervention
All subjects will receive treatment with intermittent theta burst stimulation (iTBS). There will be a total of 5 treatments over a 2-week period. All subjects will receive iTBS to the right TGd region. TBS treatment will also be provided for two additional sites within the large-scale brain networks (LSBNs) that is found to contain the greatest number of connectivity anomalies. Total participation will be 10-12 weeks.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Intermittent theta burst stimulation
2022
Completed Phase 2
~90

Find a Location

Who is running the clinical trial?

HealthPartners InstituteLead Sponsor
184 Previous Clinical Trials
3,716,149 Total Patients Enrolled
Michael H Rosenbloom, MDPrincipal InvestigatorHealthPartners Neurology
8 Previous Clinical Trials
274 Total Patients Enrolled

Media Library

Intermittent Theta Burst Stimulation (Non-invasive Brain Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT05292222 — N/A
Alzheimer's Disease Research Study Groups: Intermittent theta burst stimulation
Alzheimer's Disease Clinical Trial 2023: Intermittent Theta Burst Stimulation Highlights & Side Effects. Trial Name: NCT05292222 — N/A
Intermittent Theta Burst Stimulation (Non-invasive Brain Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05292222 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does my profile meet the criteria to join this research endeavor?

"An individual is eligible to participate in this clinical trial if they have been diagnosed with Alzheimer's disease, are between 40 and 90 years old, and are one of the 10 individuals that need to be recruited."

Answered by AI

Are there any open enrollment periods for this clinical trial?

"Clinicaltrials.gov confirms that this trial is actively seeking participants, having been first posted on June 17th 2022 and last modified on September 27th of the same year."

Answered by AI

How many participants is this trial enrolling?

"Affirmative. According to clinicaltrials.gov, this trial is currently in the recruitment phase and searching for 10 test subjects from a single site. The study was initially posted on June 17th 2022 and last updated September 27th 2022."

Answered by AI

Does this experimental procedure accept geriatric applicants?

"As specified in the study's criteria for participation, individuals must be between 40 and 90 years of age."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Transmagnetic Stimulation Pilot in Early Stage Alzheimer's Disease
2022. "Transmagnetic Stimulation Pilot in Early Stage Alzheimer's Disease". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05292222.
~4 spots leftby Apr 2025
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