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Inhibition for Mild Cognitive Impairment (LIFUP Trial)
N/A
Waitlist Available
Led By Taylor Kuhn, MD
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 60 minutes, 1 week
Awards & highlights
LIFUP Trial Summary
This trial will study whether brain stimulation using LIFUP can improve cognitive functioning in people with mild cognitive impairment or mild Alzheimer's disease.
Eligible Conditions
- Mild Cognitive Impairment
- Deep Brain Stimulation
- Brain Scan
- Alzheimer's Disease
LIFUP Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 60 minutes, 1 week
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~60 minutes, 1 week
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
FMRI
Secondary outcome measures
Change from baseline in Brief Visual Memory Test-Revised
Change from baseline in Geriatric Anxiety Inventory (GAI)
Change from baseline in Hopkins Verbal Learning Test-Revised45 (HVLT-R)
LIFUP Trial Design
2Treatment groups
Active Control
Group I: InhibitionActive Control1 Intervention
Inhibition Paradigm: LIFUP inhibits the activity of hippocampal neurons.
Group II: ExcitationActive Control1 Intervention
Excitation Paradigm: LIFUP excites the activity of hippocampal neurons.
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Who is running the clinical trial?
University of California, Los AngelesLead Sponsor
1,529 Previous Clinical Trials
10,277,794 Total Patients Enrolled
Taylor Kuhn, MDPrincipal InvestigatorUCLA Longevity Center
Taylor P Kuhn, PhDPrincipal InvestigatorUCLA Longevity Center
3 Previous Clinical Trials
213 Total Patients Enrolled
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Eligibility Criteria:
This trial includes the following eligibility criteria:- You have good enough eyesight and hearing to be able to do cognitive tests.You have taken any experimental drugs within the past month or longer, depending on how long they stay in your body.You currently have a problem with alcohol or drug addiction, or have had a serious problem with it in the past.You have a significant illness that can cause problems with your thinking, except for mild memory problems or a history of stroke or diabetes.You have very high blood pressure that is not under control, a history of serious liver disease, severe lung problems, diabetes, or cancer.You have serious mental health conditions like bipolar disorder, schizophrenia, or untreated severe depression.You had a heart attack or have unstable heart disease in the past year.
Research Study Groups:
This trial has the following groups:- Group 1: Inhibition
- Group 2: Excitation
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are there any enrollment opportunities in this research endeavor?
"Yes, the information provided by clinicaltrials.gov elucidates that enrolment is still open at this time. This medical study was initially posted on November 10th 2018 and has been recently amended on September 2nd 2022; 8 patients are being sought after across one site."
Answered by AI
How many participants have been selected to take part in this research project?
"Affirmative. Records on clinicaltrials.gov document that this medical trial, which was first made available on November 10th 2018, is currently recruiting participants. 8 individuals are sought from the single site for inclusion in the study."
Answered by AI
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