CLINICAL TRIAL

Eccentric Biceps Flexion for Marijuana Use

Recruiting · 18+ · All Sexes · Gainesville, FL

This study is evaluating whether pain can increase alcohol and marijuana use.

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About the trial for Marijuana Use

Eligible Conditions
Alcohol Drinking · Chronic Pain · Marijuana Use

Treatment Groups

This trial involves 2 different treatments. Eccentric Biceps Flexion is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are not being studied for commercial purposes.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
Eccentric Biceps Flexion
BEHAVIORAL
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.
Concentric Biceps Flexion
BEHAVIORAL

Eligibility

This trial is for patients born any sex aged 18 and older. There are 6 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Age ≥ 21 years;
English-speaking
Self-identify as White/Caucasian or Black/African American
Own a smartphone with cellular/data plan
Regularly co-use alcohol and smoked marijuana as indicated by scores of ≥3 on item 1 of the CUDIT-R and AUDIT.
Willing and able to give informed consent
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Odds of Eligibility
Unknown<50%
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: 48 hours after exercise
Screening: ~3 weeks
Treatment: Varies
Reporting: 48 hours after exercise
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: 48 hours after exercise.
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Trial Expert
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- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Eccentric Biceps Flexion will improve 2 primary outcomes in patients with Marijuana Use. Measurement will happen over the course of 48 hours after exercise.

Alcohol demand
48 HOURS AFTER EXERCISE
Changes in motivation to use alcohol, assessed using the Alcohol Purchase Task
48 HOURS AFTER EXERCISE
Marijuana demand
48 HOURS AFTER EXERCISE
Changes in motivation to use cannabis, assessed using the Marijuana Purchase Task
48 HOURS AFTER EXERCISE

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is marijuana use?

Marijuana use is now prevalent in the general U.S. population since 1991, according to the U.S. National Survey on Drug Use and Health, a project by the Office of National Drug Control Policy (ONDCP). Among U.S. adolescents aged 13 to 17, use of marijuana tripled from 1991 to 2001. Because of its illegality, the ONDCP reports use by age and year since 1991 to track trends in use. The ONDCP's latest report (2006) included data on marijuana use from 13 to 17-year-olds.

Anonymous Patient Answer

What are the signs of marijuana use?

Marijuana use may cause a wide spectrum of problems similar to withdrawal symptoms such as anxiety, irritability, and restlessness. These problems may persist for 24 hours or longer after marijuana use, suggesting a chronic effect of cannabis use. Withdrawal may also be a potential cause for many of the side effects related to marijuana use.

Anonymous Patient Answer

What causes marijuana use?

Marijuana use seems to be dependent upon an individual's predisposition which is strongly influenced by the biological processes that occur in the brain, including genetics and environmental factors such as the quality of the mother's diet and other family factors.

Anonymous Patient Answer

How many people get marijuana use a year in the United States?

Overall around 42.3 million yearly marijuana users (approximately 1 in 20 men in the United States) can be estimated. In addition about 11 million casual users, and an additional 18 million regular MMJ users (3/10s of the total, or around 1 in 25 men per year) can be estimated. There are some potential for significant improvements if all marijuana users (both recreational and medical uses) were able to participate in screening.

Anonymous Patient Answer

Can marijuana use be cured?

Marijuana use does not seem to be a cause of relapse for many smokers. However, it might be associated with less favorable outcomes for a subgroup of smokers with cannabis dependence.

Anonymous Patient Answer

What are common treatments for marijuana use?

Marijuana can significantly improve life quality. Many of the common treatments used for ADHD and depression effectively treat marijuana use. Thus, treatment modalities must be broadly applicable to the treatment of marijuana use, including the use of psychostimulant agonists, serotonin-enhancing agonists, norepinephrine reuptake inhibitors, and dopamine agonists to suppress or treat the reinforcing and pleasurable effects of marijuana use.

Anonymous Patient Answer

What is the latest research for marijuana use?

Although these findings are preliminary, in addition to the previously published results, they suggest that marijuana use would not seem to be dangerous, and its use for the treatment of pain may be beneficial.

Anonymous Patient Answer

What are the latest developments in eccentric biceps flexion for therapeutic use?

Eccentric biceps flexion is a very effective technique for the treatment of elbow instability. There are only a few limitations. First, the tendon fibers are located at their furthest point from the joint during an eccentric contraction. So eccentric work can only stretch the tendon maximally to a certain degree. Second, a high contraction velocity and high level eccentric work are necessary to maintain the tendon lengthening. This is because eccentric work is not strong enough to stretch the tendon further, so the tendon fibers get closer to the joint. Third, it is difficult to reproduce concentric work postoperatively owing to an increase in pain over the first few weeks. The eccentric work is more difficult to perform immediately after surgery due to the pain.

Anonymous Patient Answer

Does marijuana use run in families?

Recent findings does not provide conclusive evidence that familial use of marijuana is a risk factor for developing HCC, but the majority of cases could not be partitioned with an acceptable level of confidence into familial and sporadic HCC, because of the relatively short duration of the index case and the young age of cases. Recent findings are compatible with the possibility that familial and sporadic HCC may share common environmental exposures.

Anonymous Patient Answer

Is eccentric biceps flexion typically used in combination with any other treatments?

Eccentric biceps flexion is typically utilized in conjunction with a number of other methods to correct an eccentric defect of the shoulder including the shoulder abduction. However, it appears to be often combined with no other intervention.

Anonymous Patient Answer

What does eccentric biceps flexion usually treat?

Eccentric biceps flexion may be helpful for several tendon injuries, including shoulder impingement, rotator cuff tears, and tendon entrapments. Patients should follow the standard precautions for rehabilitating an eccentric muscle contraction, and an eccentric contraction should be avoided if symptoms persist more than 2 months. The degree to which biceps contraction is eccentric should relate to the severity as well as the duration of symptoms.

Anonymous Patient Answer

What is eccentric biceps flexion?

Although it has a well-recognized usefulness, there are also risks associated with eccentric biceps flexion. A prospective study examining these risks is needed to aid in clinical evaluation of their applicability.

Anonymous Patient Answer
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