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Probiotic

Probiotic Arm for Alcohol Use Disorder

Phase 2
Waitlist Available
Led By Mollie Monnig, PhD
Research Sponsored by Brown University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 30 days
Awards & highlights

Summary

This trial is testing probiotics, which are good bacteria, to see if they can help reduce inflammation in heavy drinkers who don't have serious liver disease and aren't looking to stop drinking.

Eligible Conditions
  • Alcohol Use Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~30 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
interleukin-6 (IL-6)
lipopolysaccharide binding protein (LBP)
monocyte chemoattractant protein-1 (MCP-1)
+3 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Probiotic ArmExperimental Treatment1 Intervention
Probiotic arm
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Seed DS-01 Daily Synbiotic
2022
Completed Phase 2
~40

Find a Location

Who is running the clinical trial?

Brown UniversityLead Sponsor
459 Previous Clinical Trials
559,326 Total Patients Enrolled
National Institute on Alcohol Abuse and Alcoholism (NIAAA)NIH
815 Previous Clinical Trials
1,159,840 Total Patients Enrolled
Mollie Monnig, PhDPrincipal InvestigatorBrown University
1 Previous Clinical Trials
70 Total Patients Enrolled
~9 spots leftby Sep 2025
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