Awake Extubation for Airway Complication of Anesthesia

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Airway Complication of Anesthesia+1 More
Extubation - Procedure
Eligibility
18 - 65
All Sexes
What conditions do you have?
Select

Study Summary

This trial looks at the best way to remove a breathing tube in adults, to avoid any airway or respiratory problems.

Eligible Conditions
  • Airway Complication of Anesthesia
  • Respiratory Complications of Care

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Airway Complication of Anesthesia

Study Objectives

1 Primary · 5 Secondary · Reporting Duration: From ten minutes prior to extubation to transfer time from PACU Phase 1 to PACU Phase 2 (minimum PACU Phase 1 stay 20 minutes)

At time of transfer from PACU Phase 1 to PACU Phase 2 once PACU Phase 1 discharge criteria met, minimum of twenty minutes
Incidence and Severity of Postoperative Sore Throat
From End-of-Surgery Time (defined by surgical dressing application) to Out-of-Room Time (defined by patient physically leaving operating room), up to two hours
End-of-Surgery to Out-Of-Room Time
From ten minutes prior to extubation to transfer time from PACU Phase 1 to PACU Phase 2 (minimum PACU Phase 1 stay 20 minutes)
Peri-extubation Agitation
Peri-extubation period
Aggregate Rate of Airway and Respiratory Complications
Peri-extubation Blood Pressure
Peri-extubation Heart Rate

Trial Safety

Safety Progress

1 of 3

Other trials for Airway Complication of Anesthesia

Trial Design

2 Treatment Groups

Awake Extubation
1 of 2
Deep Extubation
1 of 2
Active Control

220 Total Participants · 2 Treatment Groups

Primary Treatment: Awake Extubation · No Placebo Group · N/A

Awake Extubation
Procedure
ActiveComparator Group · 1 Intervention: Extubation · Intervention Types: Procedure
Deep Extubation
Procedure
ActiveComparator Group · 1 Intervention: Extubation · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: from ten minutes prior to extubation to transfer time from pacu phase 1 to pacu phase 2 (minimum pacu phase 1 stay 20 minutes)

Who is running the clinical trial?

United States NavyLead Sponsor

Eligibility Criteria

Age 18 - 65 · All Participants · 5 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have a physical status of ASA 1, 2, or 3.
You are an adult aged 18 to 64 years.
You have a medical condition that makes you likely to need tracheal intubation and general anesthesia.
You have a favorable airway examination.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 28th, 2021

Last Reviewed: October 30th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.