← Back to Search

Light Therapy

LED application for Pain relief

Mount Sinai Hospital, Toronto, Canada
Targeting 2 different conditionsOsseoPulse device (Light emitting diode technology)N/AWaitlist AvailableResearch Sponsored by Mount Sinai Hospital, Canada

Study Summary

Study hypothesis: Low level laser (LED) will reduce initial bone resorption and improve primary stability of dental implant. It will also reduces post operative pain compared to patient without treatment Implant osseointegration depends on many factors including biocompatibility of implant materials, design, surface, surgical access, patient conditions, biomechanical status, and lack of primary stability. Several in vivo and in vitro studies showed the healing effect of low level laser therapy (LLLT) on bone by decreasing the initial bone resorption postoperatively and increasing the primary stability of the implant. It has also shown to have an analgesic effect intraorally when used post intraoral surgical procedures. The exact mechanism is unclear despite the fact that many hypothesis has been proposed. In our study, our goal is to present, in a randomized standardized clinical trial, the effect of LLLT on post operative implant stability assessed by resonance frequency analysis (RFA). We will assess the subjective measures of postoperative pain using visual analog scale (VAS).

Eligible Conditions
  • Implants
  • Pain relief

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediately post-op, 1, 2, 4, and 8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately post-op, 1, 2, 4, and 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Implant stability
Secondary outcome measures
Post-op analgesics

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Active Control
Group I: LED applicationActive Control1 Intervention
Patients in this group will be given the LED device and will be instructed on how and when to use it. They will receive LED treatment to the surgical site preoperatively by the surgeon for 20 minutes. Then, patients in this group will apply LED at home to the surgical site postoperatively at the day of surgery and for the following 9 postoperative days.
Group II: No LED applicationActive Control1 Intervention
These patients will receive conventional dental implant treatment without the application of the LED therapy.

Find a Location

Who is running the clinical trial?

Mount Sinai Hospital, CanadaLead Sponsor
192 Previous Clinical Trials
67,248 Total Patients Enrolled
Cameron Clokie, DDS, FRCSStudy DirectorUniversity of Toronto/Mount Sinai Hospital

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
South Carolina
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
What site did they apply to?
Mount Sinai Hospital

Why did patients apply to this trial?

I’m very interested. I have very bad teeth, no dentist insurance and can’t afford, so depressed about my teeth and starting looking for clinical trails, that may help my situation.
PatientReceived 1 prior treatment
Need full mouth implants dont have the financial ability to pay for them but id rather keep my bad teeth then to get dentures i want to be able to smile and feel confident.
PatientReceived 2+ prior treatments
~4 spots leftby Nov 2024