cognitive training for Aging

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
McKnight Brain Institute, Gainesville, FL
Aging
cognitive training - Behavioral
Eligibility
65+
All Sexes
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Study Summary

The current study will investigate methods for enhancing cognitive training (CT) effects in healthy older adults by employing a combination of interventions facilitating neural plasticity and optimizing readiness for learning. A pilot randomized clinical trial will examine the individual and combined impact of pairing cognitive training with transcranial direct current stimulation (tDCS). A precision dosing algorithm will be used to determine the appropriate levels of current and location of electrodes to deliver current using tDCS.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: Baseline to post test. Post test will occur approximately two weeks following baseline.

Baseline to post test. Post test will occur approximately two weeks following baseline.
N-Back working memory

Trial Safety

Trial Design

2 Treatment Groups

Optimized tDCS + Cognitive Training
1 of 2
Sham tDCS + Cognitive Training
1 of 2
Experimental Treatment
Non-Treatment Group

40 Total Participants · 2 Treatment Groups

Primary Treatment: cognitive training · Has Placebo Group · N/A

Optimized tDCS + Cognitive TrainingExperimental Group · 2 Interventions: cognitive training, tDCS · Intervention Types: Behavioral, Device
Sham tDCS + Cognitive TrainingShamComparator Group · 2 Interventions: cognitive training, tDCS · Intervention Types: Behavioral, Device
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
cognitive training
2009
N/A
~410
tDCS
2017
Completed Phase 2
~730

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline to post test. post test will occur approximately two weeks following baseline.
Closest Location: McKnight Brain Institute · Gainesville, FL
Photo of Gainesville 1Photo of Gainesville 2Photo of florida 3
2004First Recorded Clinical Trial
1 TrialsResearching Aging
3 CompletedClinical Trials

Who is running the clinical trial?

University of FloridaLead Sponsor
1,228 Previous Clinical Trials
696,403 Total Patients Enrolled
27 Trials studying Aging
3,430 Patients Enrolled for Aging
Soterix MedicalIndustry Sponsor
9 Previous Clinical Trials
332 Total Patients Enrolled

Eligibility Criteria

Age 65+ · All Participants · 5 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.