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High Oleic Acid/Low Palmitic Acid Diet (HOA) for Aging

N/A

Waitlist Available

Led By Julie Dumas, Ph.D.

Research Sponsored by University of Vermont

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

"Healthy" (body mass index (BMI) of 20-40 kg/m2)

Men and women age range 65-75 years

Timeline

Screening 3 weeks

Treatment Varies

Follow Up after 7 days of each diet

Awards & highlights

Study Summary

This trial will study how different types of fats in the diet affect brain functioning in healthy adults aged 65-75 years. Participants will be given two different diets, one with a high ratio of pal

Who is the study for?

This trial is for healthy older adults aged 65-75 who want to participate in a study on how different fats in the diet affect brain function. Participants will follow strict diets provided by the research team and be closely monitored.Check my eligibility

What is being tested?

The study tests two diets: one high in palmitic acid, like a typical North American diet, and another high in oleic acid, similar to the Mediterranean Diet. Each participant tries both for one week with a low-fat control diet before each test period.See study design

What are the potential side effects?

Since this trial involves dietary changes rather than medication, side effects may include digestive discomfort or changes in energy levels as the body adjusts to new types of fat intake.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My BMI is between 20 and 40.

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I am between 65 and 75 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ after 7 days of each diet

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~after 7 days of each diet

This trial's timeline: 3 weeks for screening, Varies for treatment, and after 7 days of each diet for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Working Memory Brain Activation

Working Memory Brain Functional Connectivity

Working Memory Performance

Trial Design

2Treatment groups

Experimental Treatment

Group I: High Palmitic Acid Diet (HPA)Experimental Treatment1 Intervention

Participants will ingest the HPA diet for one week. The saturated fatty acid will be high in palmitic acid which is the most prevalent saturated fatty acid in the American diet. The HPA diet will be proceeded by a one week controlled diet were the fat content is balanced between monounsaturated and saturated fatty acids.

Group II: High Oleic Acid/Low Palmitic Acid Diet (HOA)Experimental Treatment1 Intervention

Participants will ingest the HOA diet for one week. The monounsaturated fatty acid will be high in oleic acid which is the most prevalent monounsaturated fatty acid in the Mediterranean diet. The HOA diet will be proceeded by a one week controlled diet were the fat content is balanced between monounsaturated and saturated fatty acids.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of VermontLead Sponsor

266 Previous Clinical Trials

3,743,631 Total Patients Enrolled

1 Trials studying Aging

120 Patients Enrolled for Aging

Julie Dumas, Ph.D.Principal InvestigatorUniversity of Vermont

Craig L Kien, MD, PhDPrincipal InvestigatorUniversity of Vermont

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are individuals currently being admitted to participate in this trial?

"According to the information provided on clinicaltrials.gov, this particular study is not actively seeking participants. The trial was originally posted on April 1st, 2024 and last updated on December 20th, 2023. However, it's worth noting that there are currently 224 other studies available for enrollment at this time."

Answered by AI

Are individuals above the age of 80 eligible to participate in this study's patient recruitment process?

"To participate in this clinical trial, potential candidates must be between the ages of 65 and 75. There are a total of 217 studies available for patients above the age of 65, while only one study is currently open for individuals under the age of 18."

Answered by AI

Which individuals meet the criteria to be considered as potential candidates for enrollment in this trial?

"To be eligible for this study, potential participants must fall within the age range of 65 to 75 years old. The trial aims to enroll approximately 60 individuals."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Fatty Acid Modulation of Brain Function in Older Adults

Julie Dumas 2024. "Fatty Acid Modulation of Brain Function in Older Adults". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06192407.

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