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THRIVE Program for HIV/AIDS

N/A

Waitlist Available

Research Sponsored by Baylor College of Medicine

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

HIV infected;

at least 18 years of age;

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

Study Summary

This trial will test a new intervention designed to help people with HIV who have missed appointments and fallen out of care to re-engage in care and stay on track.

Who is the study for?

THRIVE is for adults over 18 with HIV who aren't consistently in care, have a viral load over 1000 c/mL, and use avoidance coping strategies. They must be hospitalized at Ben Taub Hospital, Houston, TX, speak English or Spanish, and can consent to participate. Excluded are those incarcerated, pregnant women or involved in other studies.Check my eligibility

What is being tested?

The THRIVE trial is testing a new intervention aimed at improving outpatient HIV care engagement post-hospitalization for patients practicing avoidance. It compares the effectiveness of usual treatment against the THRIVE program to see if it helps reduce viral loads and improve retention in care.See study design

What are the potential side effects?

Since this trial focuses on an engagement intervention rather than medication, traditional side effects like those seen with drugs are not applicable here. However, participants may experience emotional or psychological discomfort discussing their condition.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am HIV positive.

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I am 18 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Acceptability of enrollment and randomization

Acceptability of the intervention

Secondary outcome measures

Number of patients who are retained in HIV Care

Viral Load Improvement

Other outcome measures

Alcohol Use Disorders Identification Test (AUDIT)

Client Satisfaction Questionnaire (CSQ)

Coping with HIV/AIDS scale

+3 more

Trial Design

2Treatment groups

Experimental Treatment

Group I: Treatment as UsualExperimental Treatment1 Intervention

Patients get usual care at the hospital. Service linkage workers (SLWs) meet with all hospitalized PWH and cover educational aspects of the care.

Group II: THRIVEExperimental Treatment1 Intervention

Acceptance and Commitment Therapy plus Education about HIV A master's level mental health professional will provide the 4-5 hour intervention for out-of-care PWH during a hospitalization. There are two important components to the intervention: Acceptance and Commitment Therapy (ACT) content, targeting avoidance with acceptance-based coping and active engagement in values-based living, and HIV education.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

THRIVE

2017

N/A

~350

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Baylor College of MedicineLead Sponsor

1,001 Previous Clinical Trials

6,001,877 Total Patients Enrolled

University of IowaOTHER

446 Previous Clinical Trials

879,427 Total Patients Enrolled

Brown UniversityOTHER

456 Previous Clinical Trials

563,006 Total Patients Enrolled

Media Library

THRIVE Clinical Trial Eligibility Overview. Trial Name: NCT04481373 — N/A

HIV/AIDS Research Study Groups: THRIVE, Treatment as Usual

HIV/AIDS Clinical Trial 2023: THRIVE Highlights & Side Effects. Trial Name: NCT04481373 — N/A

THRIVE 2023 Treatment Timeline for Medical Study. Trial Name: NCT04481373 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is access to this research experiment currently available for participants?

"Clinicaltrials.gov's data affirms that this clinical trial, which was initially posted on March 3rd 2021 and last edited February 28th 2022, is no longer recruiting patients. However, there are presently 1,958 other medical studies actively looking for volunteers."

Answered by AI

Is the eligibility range for this experiment limited to individuals younger than 35 years old?

"According to the eligibility requirements, potential participants must be 18 years old and at most 80. Those who are younger than 18 have access to 366 trials while those over 65 can explore 1447 different studies."

Answered by AI

Are there any specific criteria that make someone an ideal participant in this clinical experiment?

"This investigation is looking to enrol 80 individuals between 18 and 80 years of age who have depression. Furthermore, in order to take part in the trial participants must be capable of consenting; hospitalised at Ben Taub Hospital (in Houston, TX); able to speak either English or Spanish fluently; HIV positive with a viral load greater than 1000 c/mL; never having received treatment for their infection or currently not receiving any care as defined by missing two appointments within the last year at Thomas Street Health Center (Houston, TX) plus endorsing one of two avoidance coping statements from the Coping With HIV/AIDS scale's Avoidant Coping"

Answered by AI

Recent research and studies

Journal of Clinical MedicineJournal

Development and Initial Feasibility of a Hospital-based Acceptance and Commitment Therapy Intervention to Improve Retention in Care for Out-of-care Persons with HIV: Lessons Learned from an Open Pilot Trial

Dindo, Lilian, Ethan Moitra, McKenzie K. Roddy, Chelsea Ratcliff, Christine Markham, and Thomas Giordano. 2022. “Development and Initial Feasibility of a Hospital-based Acceptance and Commitment Therapy Intervention to Improve Retention in Care for Out-of-care Persons with HIV: Lessons Learned from an Open Pilot Trial”. Journal of Clinical Medicine. MDPI AG. doi:10.3390/jcm11102827.

clinicaltrials.govStudy

Targeting HIV Retention and Improved Viral Load Through Engagement ('THRIVE')

Thomas Giordano 2021. "Targeting HIV Retention and Improved Viral Load Through Engagement ('THRIVE')". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04481373.

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