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Brain Stimulation

rTMS for Navigation Ability in Healthy Subjects

N/A
Recruiting
Led By Daniel Dilks, PhD
Research Sponsored by Emory University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline (rtms of control site) and during rtms of opa, on day 1
Awards & highlights

Study Summary

This trial uses rTMS to disrupt particular brain regions to study how they may aid in visually-guided navigation.

Who is the study for?
This trial is for healthy adults with normal or corrected-to-normal vision. It's not suitable for those with metal in their body, a personal or family history of seizures, known brain injury, on specific medications (like bupropion or benzodiazepines), claustrophobic individuals, those unable to consent, pregnant women, and prisoners.Check my eligibility
What is being tested?
The study uses repetitive Transcranial Magnetic Stimulation (rTMS) to understand how the brain helps people navigate spaces like rooms without bumping into things. Participants will have certain brain areas temporarily disrupted while they perform computer tasks or simple actions based on visual cues.See study design
What are the potential side effects?
While rTMS is generally considered safe for healthy individuals, it can sometimes cause discomfort at the stimulation site, headache, lightheadedness or even induce a seizure; though this last side effect is extremely rare.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline (rtms of control site) and during rtms of opa, on day 1
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline (rtms of control site) and during rtms of opa, on day 1 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Performance During Visually-guided Navigation Behavioral Task
Change in Performance During Visually-guided Navigation Computer Task

Trial Design

1Treatment groups
Experimental Treatment
Group I: Repetitive Transcranial Magnetic Stimulation (rTMS)Experimental Treatment1 Intervention
Participants will have two study visits. During the first visit, participants will have an fMRI scan to identify the OPA location in each individual participant. During the second visit, participants will receive rTMS. Each visit lasts approximately 90 minutes.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Repetitive Transcranial Magnetic Stimulation (rTMS)
2019
Completed Phase 2
~780

Find a Location

Who is running the clinical trial?

Emory UniversityLead Sponsor
1,640 Previous Clinical Trials
2,560,658 Total Patients Enrolled
National Eye Institute (NEI)NIH
547 Previous Clinical Trials
1,402,119 Total Patients Enrolled
Daniel Dilks, PhDPrincipal InvestigatorEmory University

Media Library

rTMS (Brain Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT04961645 — N/A
Healthy Subjects Research Study Groups: Repetitive Transcranial Magnetic Stimulation (rTMS)
Healthy Subjects Clinical Trial 2023: rTMS Highlights & Side Effects. Trial Name: NCT04961645 — N/A
rTMS (Brain Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04961645 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there room for more participants in this medical experiment?

"According to the data available on clinicaltrials.gov, this medical trial is not recruiting participants at present. It was initially posted in January 1st 2023 and last updated in June 1st 2022; however, there are 839 other studies actively searching for enrollees as of now."

Answered by AI

Who else is applying?

What state do they live in?
Georgia
How old are they?
18 - 65
What site did they apply to?
Emory University
What portion of applicants met pre-screening criteria?
Met criteria

Why did patients apply to this trial?

Looking to further MRI technology.
PatientReceived 2+ prior treatments
Recent research and studies
clinicaltrials.govStudy
Brain Stimulation and Visually-guided Navigation
Daniel Dilks 2023. "Brain Stimulation and Visually-guided Navigation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04961645.
~16 spots leftby Feb 2025
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