Physical Activity for Childhood Cancer Survivors

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Childhood Cancer Survivors+1 More
Physical Activity - Behavioral
Eligibility
< 18
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test the effects of a 12-week physical activity intervention on 10-17 year-olds who have had cancer, to see if it improves patient reported outcomes and physical function.

Eligible Conditions
  • Childhood Cancer Survivors
  • Childhood Cancers

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 13 Secondary · Reporting Duration: Week 12

Baseline
Acceptability-the proportion of adolescents and young adults who agree to participate
Baseline to week 12
Costs
Feasibility-the proportion of adolescents and young adults who complete at least 50% of the physical activity intervention
Week 12
Patient reported outcomes-anxiety
Patient reported outcomes-depressive symptoms
baseline
Demographics
post-intervention (week 13)
Accelerometry
week 12
Patient reported outcomes-cognitive function
Patient reported outcomes-fatigue
Patient reported outcomes-pain intensity
Patient reported outcomes-pain interference
Patient reported outcomes-peer relationships
Patient reported outcomes-physical function mobility
Patient reported outcomes-sleep disturbance
Patient reported outcomes-social isolation
Physical activity-Godin-Shephard Leisure-Time Physical Activity Questionnaire (process outcome)
Physical activity-International physical activity questionnaire (process outcome)
physical function-30 second chair stand
physical function-six minute walking test
physical function-timed up and go

Trial Safety

Safety Progress

1 of 3

Trial Design

1 Treatment Group

Physical activity intervention group
1 of 1
Experimental Treatment

40 Total Participants · 1 Treatment Group

Primary Treatment: Physical Activity · No Placebo Group · N/A

Physical activity intervention group
Behavioral
Experimental Group · 1 Intervention: Physical Activity · Intervention Types: Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Physical Activity
2019
Completed Phase 3
~4650

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: week 12

Who is running the clinical trial?

Four Diamonds Research Fund at Penn State Health Childrens HospitalUNKNOWN
1 Previous Clinical Trials
20 Total Patients Enrolled
1 Trials studying Childhood Cancer Survivors
20 Patients Enrolled for Childhood Cancer Survivors
Milton S. Hershey Medical CenterLead Sponsor
455 Previous Clinical Trials
2,784,246 Total Patients Enrolled
1 Trials studying Childhood Cancer Survivors
20 Patients Enrolled for Childhood Cancer Survivors
Kathryn Schmitz, PhDPrincipal InvestigatorMilton S. Hershey Medical Center
10 Previous Clinical Trials
1,710 Total Patients Enrolled
Smita Dandekar, MDPrincipal InvestigatorMilton S. Hershey Medical Center
2 Previous Clinical Trials
40 Total Patients Enrolled
1 Trials studying Childhood Cancer Survivors
20 Patients Enrolled for Childhood Cancer Survivors

Eligibility Criteria

Age < 18 · All Participants · 9 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
At least 1 year and up to 5 years post-treatment.\n
You can speak, read and understand the English language.\n

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 29th, 2021

Last Reviewed: October 15th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.