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Nicotine Replacement Therapy

High Strength, Low Strength for Vaping

N/A

Waitlist Available

Research Sponsored by Yale University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 210 minutes

Awards & highlights

Study Summary

This trial will test if e-cigarettes provide efficient nicotine delivery to the brain and arterial blood in smokers and e-cigarette users, and if the liquid characteristics of e-cigarettes modulate this effect.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 210 minutes

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~210 minutes

This trial's timeline: 3 weeks for screening, Varies for treatment, and 210 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Brain beta-2 nicotinic acetylcholine receptor occupancy

Secondary outcome measures

Maximum arterial blood nicotine

Trial Design

2Treatment groups

Experimental Treatment

Group I: Low Strength, High StrengthExperimental Treatment2 Interventions

Group II: High Strength, Low StrengthExperimental Treatment2 Interventions

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Yale UniversityLead Sponsor

1,847 Previous Clinical Trials

2,737,668 Total Patients Enrolled

2 Trials studying Vaping

295 Patients Enrolled for Vaping

National Institute on Drug Abuse (NIDA)NIH

2,465 Previous Clinical Trials

2,618,633 Total Patients Enrolled

10 Trials studying Vaping

5,072 Patients Enrolled for Vaping

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the criteria for inclusion in this clinical investigation?

"To be considered for this study, participants must have prior experience with e-cigarettes and fall within the age demographic of 21 to 55. The total number of enrollees is 20."

Answered by AI

How many participants are participating in this medical research?

"Affirmative, the clinicaltrials.gov website lists this trial as actively recruiting participants. First posted on December 30th 2022 and updated February 8th 2022, 20 volunteers are needed from a single location for this experiment."

Answered by AI

Could individuals below the age of thirty partake in this trial?

"This clinical trial is available to individuals aged between 21 and 55. If one falls outside of this age bracket, there are 5 studies for those under 18 years old and 59 studies targeting seniors over 65."

Answered by AI

Has any research been conducted in regards to the efficacy of various potency levels?

"Currently, 71 investigations into the efficacy of High Strength and Low Strength are being conducted worldwide. 5 trials have reached their third phase, with most taking place in Green Bay, Wisconsin. In total, 204 medical facilities are involved in this research study."

Answered by AI

Is enrollment in this experiment open to participants at the moment?

"According to the information on clinicaltrials.gov, this study is actively seeking participants. It was initially posted in late December 2022 and has been updated recently on February 8th 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Understanding Factors That Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine Receptors

2022. "Understanding Factors That Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine Receptors". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04258852.