Home-based aerobic exercise for Cognitive Aging

Q: Does this research endeavor have an age requirement, and if so, is it higher than 25 years?

The target population for this clinical trial are those aged between 30 and 55 years old.

Q: For whom is this clinical trial most suitable?

For this research study, 40 participants with cognitive aging must be enrolled. Prospective candidates should meet the prerequisites: between 30 and 55 years old, experienced a t<a href="https://www.withpower.com/clinical-trials/ra">ra</a>umatic event before age 10 according to self-reported evidence, Black or African American race, access to internet at high speeds, sedentary (less than 60 minutes of physical activity per week), no mobility limitations, not using any assistive walking tools like canes or walkers currently, no balance problems in history, not expecting <a href="https://www.withpower.com/clinical-trials/pregnancy">pregnancy</a> within next 12 months.

Q: Are there still opportunities to join this research trial?

Affirmative. As indicated on clinicaltrials.gov, this research is presently enrolling participants with an initial post date of January 4th 2022 and most recent update on October 6th 2022. The endeavour seeks to recruit 40 patients from 3 distinct sites.

Q: What is the enrollment size of this research endeavor?

Affirmative. The information found on clinicaltrials.gov asserts that this experiment is currently enrolling participants, with the first post being made on April 1st 2022 and a recent update occurring on October 6th of the same year. Forty patients need to be recruited from three distinct medical sites.

Q: What aims is this medical experiment attempting to achieve?

This study is set to evaluate a particular exercise intervention program over the course of 12 weeks. The primary outcome being measured will be average duration of sessions, while secondary outcomes include changes in picture sequence performance, picture vocabulary performance and flanker task performance - <a href="https://www.withpower.com/clinical-trials/all">all</a> indicative or worse cognitive ability with lower numbers indicating poorer results.

Chelsea Stillman, Pittsburgh, PA

Targeting 2 different conditionsHome-based aerobic exercisePhase < 1Waitlist AvailableLed by Kirk I Erickson, PhDResearch Sponsored by University of Pittsburgh

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Exposure to at least one form of threat-related adversity (e.g., exposure to violence; physical abuse) occurring prior to age 10 as documented by retrospective self-report

Sedentary lifestyle (<60 minutes of PA/week)

Must not have

Be younger than 18 years old

Be older than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Upbaseline to 12 weeks

Awards & highlights

No Placebo-Only Group

Study Summary

This trial is testing a 12-week home-based exercise intervention to see if it is feasible and acceptable for Black and African American adults. They also want to see if the intervention improves cognitive and psychological functioning.

Eligible Conditions

Cognitive Aging
Adverse Childhood Experiences

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below

Select...

You have experienced some form of harmful or scary events before you were 10 years old, like witnessing violence or being physically abused, as reported by your own memories.

Select...

You don't participate in physical activities for at least 60 minutes per week.

Select...

You have never experienced problems with your balance in the past.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline to 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline to 12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Adherence to exercise intervention program: Average duration of sessions

Adherence to exercise intervention program: Average minutes spent in moderate to vigorous exercise

Adherence to exercise intervention program: Number of sessions completed

Secondary outcome measures

Mean change in Dimensional Card Sort performance

Mean change in Flanker performance

Mean change in List Sorting performance

+6 more

Other outcome measures

Mean change in heart rate

Mean change in physical activity

Mean change in systolic blood pressure

+1 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Home-based aerobic exerciseExperimental Treatment1 Intervention

Un-supervised exercise will be held 3 times a week for 60 minutes in the participant's home

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Home-based aerobic exercise

2022

Completed Early Phase 1

~10

0 / 3Eligibility criteria met

Find a site

Who is running the clinical trial?

University of PittsburghLead Sponsor

1,674 Previous Clinical Trials

16,301,954 Total Patients Enrolled

National Institutes of Health (NIH)NIH

2,611 Previous Clinical Trials

6,804,886 Total Patients Enrolled

National Institute on Aging (NIA)NIH

1,554 Previous Clinical Trials

5,220,403 Total Patients Enrolled

6 Trials studying Cognitive Aging

657 Patients Enrolled for Cognitive Aging

Kirk I Erickson, PhDPrincipal Investigator

University of Pittsburgh

4 Previous Clinical Trials

1,119 Total Patients Enrolled

Shannon D Donofry, PhDPrincipal Investigator

University of Pittsburgh

Chelsea M Stillman, PhDPrincipal Investigator

University of Pittsburgh

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research endeavor have an age requirement, and if so, is it higher than 25 years?

"The target population for this clinical trial are those aged between 30 and 55 years old."

Answered by AI

For whom is this clinical trial most suitable?

"For this research study, 40 participants with cognitive aging must be enrolled. Prospective candidates should meet the prerequisites: between 30 and 55 years old, experienced a traumatic event before age 10 according to self-reported evidence, Black or African American race, access to internet at high speeds, sedentary (less than 60 minutes of physical activity per week), no mobility limitations, not using any assistive walking tools like canes or walkers currently, no balance problems in history, not expecting pregnancy within next 12 months."

Answered by AI

Are there still opportunities to join this research trial?

"Affirmative. As indicated on clinicaltrials.gov, this research is presently enrolling participants with an initial post date of January 4th 2022 and most recent update on October 6th 2022. The endeavour seeks to recruit 40 patients from 3 distinct sites."

Answered by AI

What is the enrollment size of this research endeavor?

"Affirmative. The information found on clinicaltrials.gov asserts that this experiment is currently enrolling participants, with the first post being made on April 1st 2022 and a recent update occurring on October 6th of the same year. Forty patients need to be recruited from three distinct medical sites."

Answered by AI

What aims is this medical experiment attempting to achieve?

"This study is set to evaluate a particular exercise intervention program over the course of 12 weeks. The primary outcome being measured will be average duration of sessions, while secondary outcomes include changes in picture sequence performance, picture vocabulary performance and flanker task performance - all indicative or worse cognitive ability with lower numbers indicating poorer results."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Physical Exercise for Augmenting Cognitive Health (PEACH)

Kirk Erickson, PhD 2022. "Physical Exercise for Augmenting Cognitive Health (PEACH)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04922710.