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Dietary Intakes for Healthy Subjects

N/A
Waitlist Available
Led By Glenda Courtney-Martin, PhD
Research Sponsored by The Hospital for Sick Children
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 years
Awards & highlights

Study Summary

This trial will help researchers understand if the body needs more or less of the amino acid threonine, depending on how long it has been adapted to a certain level of intake.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Determination of threonine requirement in young adult men after 8 hours, 3, and 7 days of adaptation to experimental diets.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Healthy adult menExperimental Treatment1 Intervention
Participants will initially be seen for a pre-study assessment (2 hours). They will then be studied for up to 6 times (6 different levels of threonine intake). Each set of experiments will be 9-days in length. During the first 2 days, a pre-adaptation (milkshake) diet will be consumed. For the remaining 7 days, a protein liquid drink and protein-free cookies will be consumed. All of the diets will be provided by the investigators. During each 9-day experiment, participants are expected to come to the Clinical Research Centre at the Hospital for Sick Children for breath and urine collection (5 hours total for each visit)

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Who is running the clinical trial?

The Hospital for Sick ChildrenLead Sponsor
691 Previous Clinical Trials
6,945,603 Total Patients Enrolled
Glenda Courtney-Martin, PhDPrincipal InvestigatorThe Hospital for Sick Children
5 Previous Clinical Trials
155 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Length of Adaptation and Threonine Requirement
Glenda Courtney-Martin 2020. "Length of Adaptation and Threonine Requirement". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04585087.
~2 spots leftby May 2025
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