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Response Inhibition Training: A for Smoking Cessation

N/A
Waitlist Available
Led By Robert D Dvorak, PhD
Research Sponsored by North Dakota State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Individuals 18-45 years old, who smoke at least 10 cigarettes/day, score 5 or higher on the Fägerstrom Test of Nicotine Dependence, express a desire to quit, and have no current psychiatric diagnoses.
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months
Awards & highlights

Study Summary

The current study tests a response inhibition retraining program, implemented on a mobile device, as a mechanism to increase relapse prevention during a smoking cessation attempt. Study participants (n = 150) are randomly assigned to a control, benign, or intervention condition. They complete 2 weeks of response inhibition retraining, and then engage in a cessation attempt. It is hypothesized that individuals who receive the intervention will have a decreased likelihood of relapse following the cessation attempt. In addition, it is hypothesized that this is due to decreases in implicit smoking motivation as a function of the response inhibition training.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Smoking relapse

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: Response Inhibition Training: AExperimental Treatment1 Intervention
In the experimental condition, 20% of responses are no-go, with the majority of no-go responses paired with smoking images.
Group II: Response Inhibition Training: BActive Control1 Intervention
In the active comparator condition, 20% of responses are no-go trials, with no-go responses spread evenly across the various images.
Group III: BenignPlacebo Group1 Intervention
A benign condition has also been added to control for the possibility that response inhibition training, regardless of target, increases behavioral control and hence decreases relapse likelihood. The benign condition has 50% no-go trials, with no-go responses spread evenly across images.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Response Inhibition Training
2014
N/A
~30

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Who is running the clinical trial?

North Dakota State UniversityLead Sponsor
21 Previous Clinical Trials
687 Total Patients Enrolled
Robert D Dvorak, PhDPrincipal InvestigatorAmy Scott, PhD

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Smoking Response Inhibition Training
2014. "Smoking Response Inhibition Training". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02218944.
All > Smoking
~14 spots leftby Apr 2025
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