Treatment for Enteral Feeding

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Mayo Clinic, Rochester, MN
Enteral Feeding
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a high protein enteral formula is safe and effective for people with advanced dementia.

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Treatment Effectiveness

Study Objectives

This trial is evaluating whether Treatment will improve 1 primary outcome and 4 secondary outcomes in patients with Enteral Feeding. Measurement will happen over the course of 14 days.

14 days
Adverse events
Calorie nutritional goals
Daily reports of gastrointestinal intolerance
Intolerance markers
Protein nutritional goals

Trial Safety

Trial Design

0 Treatment Group

This trial requires 30 total participants across 0 different treatment group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 14 days
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 14 days for reporting.

Closest Location

Mayo Clinic - Rochester, MN

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
The text is saying that the person is anticipated to need enteral nutrition in order to provide 90% or more of their nutritional needs. show original
Adults with established enteral access
Signed informed consent

Patient Q&A Section

Can enteral feeding be cured?

"Enteral feeding is not cured. However, it has little effect on symptoms, quality of life, or social relationships. Patients should be encouraged to maintain a healthy diet, exercise, and maintain normal weight." - Anonymous Online Contributor

Unverified Answer

What causes enteral feeding?

"The precise aetiology for enteral feeding remains unknown, but this may have multiple etiologies including: anatomical and muscular abnormalities, intestinal motility abnormalities, and an inability of the mucosal lining to express adequate quantities of mucus." - Anonymous Online Contributor

Unverified Answer

How many people get enteral feeding a year in the United States?

"Based on nationally representative sample data, about 10% of children under the age of 2 years received enteral feedings during 2000. By the age of 2 years, this rate had increased to about 28%. The rate of enteral feeding increased steadily from 2000 to 2004, with 42% of children currently receiving enteral feeding. Growth of enteral feeding use has been slower for children under 2 years. Additional efforts are needed to improve enteral feeding use in this vulnerable population." - Anonymous Online Contributor

Unverified Answer

What are the signs of enteral feeding?

"Feeding intolerance can be diagnosed by observing the signs that arise in patients who are not able to swallow. Signs that arise include vomiting, regurgitation, abdominal pain, and vomiting of blood. Feeding intolerance is common in patients that are critically ill.  It occurs especially often in patients that were critically ill neonates.   Additionally, symptoms of nausea and vomiting are often present in patients that are being fed.  So it seems that patients can be fed, but that this could not always be possible." - Anonymous Online Contributor

Unverified Answer

What are common treatments for enteral feeding?

"The treatment of intestinal feeding or percutaneous jejunal feeding is currently recommended for patients with acute or post-operative abdominal pain in the hospital setting. But there is not sufficient evidence for clinical practice to recommend either or both methods for patients in the subacute and chronic care setting or for those with other conditions that can contribute to an anorexia and dehydration such as cancer, cardiovascular disease and sepsis. Additional randomized controlled trials are needed to confirm the appropriateness of enteral feeding and PNJ method in either the hospital or subacute or chronic care setting." - Anonymous Online Contributor

Unverified Answer

What is enteral feeding?

"The gastrointestinal tract is a complex system that exists over 30 feet long and has many functions including the generation and absorption of nutrients, regulation of fluid balance and the control of the immune system. Nutrients are absorbed through the gut wall, enter the bloodstream in small quantities, and eventually move into the tissues, where they provide energy for growth and repair of the body and the brain. Enteral nutrition is one of the most effective means by which to maintain an appropriate nutrient flow to the body. It is used around the world to support health, enhance function and optimize the person's overall quality of life as well as to help people who have trouble with it." - Anonymous Online Contributor

Unverified Answer

What is treatment?

"Gastric feeding is technically simple and safe and is a reasonable parenteral method to treat dehydration from a wide variety of causes, ranging from simple vomiting to severe pancreatitis. However, one should also note that gastric feeding can also induce nausea and vomiting." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in treatment for therapeutic use?

"Therapeutic use is increasingly used to support nutrition. However, a significant proportion of patients have complications of the treatment that need to be addressed. In particular patients need to be adequately informed of these adverse effects and given treatment options." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating enteral feeding?

"There are some interesting recent developments on the theory of the mechanism of intestinal absorption of nutrients and the effect on the intestinal villi. In fact, the latest results show that enteral feeding can contribute to the proliferation of the intestinal crypt epithelial cells and to the differentiation of enterocytes on the villi." - Anonymous Online Contributor

Unverified Answer

Have there been other clinical trials involving treatment?

"These trials would include, in particular, clinical trials of nonprescription and/or nontoxic drugs in the treatment of patients with chronic gastrointestinal diseases, such as functional bowel disorders, and in the clinical management of digestive tract infections, with drugs like paracetamol, parasympathomimetics like catecholamines, or nonsteroidal anti-inflammatory drugs like piroxicam for improving motility, or a prokinetic such as domperidone, for improving motility through vagal stimulation, and for decreasing postprandial cramping." - Anonymous Online Contributor

Unverified Answer

What is the latest research for enteral feeding?

"This article brings up some of the key findings of recent studies into enteral feeding. It is clear from the latest evidence that the use of enteral feeding and short bowel syndrome are two very different diseases requiring different treatments." - Anonymous Online Contributor

Unverified Answer

Is treatment typically used in combination with any other treatments?

"The majority of patients in this study were treated with chemotherapy. The most common regimen consisted of either vincristine, cyclophosphamide, or epirubicin followed by doxorubicin and other agents. The treatment used had no effect on the incidence, course, and pattern of progression of the disease." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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