Neurofeedback for Attention Deficit Hyperactivity Disorder (ADHD)

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Stanford University School of Medicine, Stanford, CA
Attention Deficit Hyperactivity Disorder (ADHD)
Neurofeedback - Behavioral
Eligibility
< 18
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a new type of computerized training may help improve working memory for children with attention deficit hyperactivity disorder.

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Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Neurofeedback will improve 2 primary outcomes, 4 secondary outcomes, and 3 other outcomes in patients with Attention Deficit Hyperactivity Disorder (ADHD). Measurement will happen over the course of baseline and 6 weeks.

baseline and 6 weeks
Change in Behavior Rating Inventory of Executive Function (BRIEF), Working Memory t-score
Change in California Verbal Learning Test - Children's version (CVLT-C) score
Change in Conners 3rd Edition ADHD Index and Inattention t-score
Change in Continuous Performance Test (CPT) accuracy
Change in Developmental NEuroPSYchological Assessment II (NEPSY-II) composite score
Change in Parent Stress Index 4th Edition (PSI-IV)
Change in Wide Range Assessment of Memory and Learning 2 (WRAML-2), General Memory Index score
Week 6
Change in target frontal-parietal activity
Change in working memory performance

Trial Safety

Safety Estimate

1 of 3

Trial Design

3 Treatment Groups

Cognitive Training
1 of 3
Waitlist
1 of 3
Neurofeedback
1 of 3
Active Control
Experimental Treatment

This trial requires 60 total participants across 3 different treatment groups

This trial involves 3 different treatments. Neurofeedback is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Neurofeedback
Behavioral
The Neurofeedback group will receive 12 sessions of computerized cognitive intervention combined with neurofeedback in the lab.
Cognitive Training
Behavioral
The Cognitive Training group will receive 12 sessions of computerized cognitive intervention in the lab.
WaitlistBoth Neurofeedback and Cognitive Training groups will be assigned to waitlist before starting the corresponding intervention.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Neurofeedback
2016
Completed Phase 3
~690

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 3 and 6 weeks
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly baseline, 3 and 6 weeks for reporting.

Who is running the study

Principal Investigator
H. H.
Prof. Hadi Hosseini, Assistant Professor
Stanford University

Closest Location

Stanford University School of Medicine - Stanford, CA

Eligibility Criteria

This trial is for patients born any sex aged 18 and younger. There are 5 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
This text is about the age range from 7 to 11 years show original
There is no one-size-fits-all answer to this question, as the diagnosis and/or current symptoms of ADHD can vary depending on the individual show original
This individual has a high working memory score on the BRIEF. show original
The following are allowed comorbidities: oppositional defiant disorder, learning disabilities excluding dyslexia, and mild anxiety and/or depression. show original
A person has a full-scale intelligence quotient (IQ) if it is ≥80. show original

Patient Q&A Section

What are common treatments for attention deficit hyperactivity disorder (adhd)?

"There are many different treatments available for ADHD, including medication, speech therapy, occupational therapy, and psychotherapy. Treatment should be tailored to the specific needs of the patient and may vary according to the severity and the comorbidities of the disease. There is no single best treatment for ADHD. Treatment may vary for most and even a majority of the patients depending on the severity and co-morbidities of the disease." - Anonymous Online Contributor

Unverified Answer

What are the signs of attention deficit hyperactivity disorder (adhd)?

"The symptoms of a diagnosis of ADHD may be expressed across many symptoms of comorbid disorders, including the signs of anxiety, mood, and behavioural problems. This adds to the complexity of distinguishing comorbid mood disorders, or psychiatric disorders that are comorbid with ADHD, such as eating disorders and/or somatoform disorders." - Anonymous Online Contributor

Unverified Answer

How many people get attention deficit hyperactivity disorder (adhd) a year in the United States?

"ADHD affects 7% of adults and 3.1% of children. The percentage of people with ADHD seems to be stable over years. The prevalence of ADHD seems greatest in children and declines with age in adults." - Anonymous Online Contributor

Unverified Answer

Can attention deficit hyperactivity disorder (adhd) be cured?

"A diagnosis of AHD has an estimated prevalence of 0.5%-1% among students in primary school. A significant proportion of people with AHD do not have major psychiatric symptoms. Thus, AHD must be considered when estimating the prevalence of ADHD." - Anonymous Online Contributor

Unverified Answer

What is attention deficit hyperactivity disorder (adhd)?

"Attention is a multisystem concept, having links with many physiological, psychological, and cognitive processes, which underlie normal behaviours. While it is not surprising that ADHD features are frequent in psychiatric disorders, many such disorders are also marked by the same symptom symptoms, and the clinical and cognitive features of ADHD are more similar to those of other disorders such as depression, schizophrenia, and ADHD is more accurately referred to as a syndrome and has been shown in numerous studies to be a continuum with the neurocognitive profiles of patients at risk for depression and ADHD. Attention deficiency is not an essential part of ADHD, but people with it struggle, often for decades, with everyday problems. In childhood and adulthood ADHD features are associated with a number of disorders." - Anonymous Online Contributor

Unverified Answer

What causes attention deficit hyperactivity disorder (adhd)?

"Adults with ADHD manifest many symptoms resembling ADHD in children. Adolescents with ADHD are similar to older children in age and gender, and they share the same symptoms in both genders." - Anonymous Online Contributor

Unverified Answer

What is the latest research for attention deficit hyperactivity disorder (adhd)?

"There is a growing number of clinical trials that are attempting to look at the effects of different options at treating ADHD. Attention deficit hyperactivity disorder research has been a growing target for researchers, and more research is needed to continue to help treat the symptoms of this disease." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in neurofeedback for therapeutic use?

"This article is an example of how neurofeedback has advanced the therapeutic applications of this technology and how the technology and methods for creating an experience have also progressed. Neurofeedback can be a useful tool for treating attention deficit hyperactivity disorder and may also help to reduce the debilitating symptoms of phantom limb syndrome." - Anonymous Online Contributor

Unverified Answer

How serious can attention deficit hyperactivity disorder (adhd) be?

"The present results suggest that children with adhd have deficits in attention, which are significant for all domains of cognitive performance. Attention skills are important in educational settings, and children with adhd may benefit from a comprehensive educational program." - Anonymous Online Contributor

Unverified Answer

Have there been other clinical trials involving neurofeedback?

"Although many studies have used the terms neurofeedback and neurotherapy, only three published studies have measured neurocognitive and psychophysiological response to this treatment method. Although the use of neurofeedback in a clinical setting is still evolving, the evidence, from these three studies, supports this method as a therapeutic tool for improving the well-being of patients." - Anonymous Online Contributor

Unverified Answer

Has neurofeedback proven to be more effective than a placebo?

"We found no difference in EEG or cognitive improvement between the active and the control group. This preliminary analysis was limited by two open uncontrolled studies with low sample size, lack of data on blinding or randomization procedures." - Anonymous Online Contributor

Unverified Answer

Does neurofeedback improve quality of life for those with attention deficit hyperactivity disorder (adhd)?

"The effects of an 8-week neurofeedback training program on the ADHD symptoms indicated that an additional treatment period of 2 months of neurofeedback can lead to improvements in patients' ADHD symptoms and quality of life." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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