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Not Applicable

Neuromuscular Rehabilitation for ACL Injury Prevention in Athletes

N/A
Recruiting
Led By Nathaniel Bates, PhD
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
No low back or lower extremity injury in the year prior to ACL injury necessitating medical care
Age, 13 to 30 years
Timeline
Screening 3 weeks
Treatment Varies
Follow Up all 5 years of study
Awards & highlights

Study Summary

This trial is looking to see if they can reduce the risk of second ACL injury in athletes by identifying risk groups and giving them different rehabilitation protocols.

Who is the study for?
This trial is for active athletes aged between 14 and 24 who have had their first ACL injury within the last 6 months. They should not have had previous knee surgeries, complex meniscus tears, or other recent injuries that required medical care. Participants must have been involved in sports requiring cutting, jumping, or pivoting for at least 50 hours a year.Check my eligibility
What is being tested?
The study aims to reduce second ACL injuries by identifying high-risk individuals based on movement patterns and testing different rehab protocols after initial ACL reconstruction. The interventions being tested are HOME (home-based exercises) and TNMT (targeted neuromuscular training).See study design
What are the potential side effects?
While specific side effects are not listed for this type of intervention, participants may experience general discomfort, muscle soreness, fatigue from exercises or potential aggravation of knee symptoms during rehabilitation.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I haven't had a lower back or leg injury requiring medical care in the year before my ACL injury.
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I am between 13 and 30 years old.
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I have a recent (less than 6 months) first-time ACL injury.
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I have never had knee surgery on either leg.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~all 5 years of study
This trial's timeline: 3 weeks for screening, Varies for treatment, and all 5 years of study for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Second ACL Injury
Secondary outcome measures
Frontal plane knee kinematics
Frontal plane knee kinetics

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: TNMTExperimental Treatment1 Intervention
Patients who are enrolled in the TNMT group will participate in 12 sessions of supervised outpatient physical therapy over a six week period. The TNMT protocol is distinguished by performance of exercises designed to enhance core and hip strength, performance of neuromuscular training exercise that are designed to correct movement flaws associated with second ACL injury25, providing verbal and visual feedback and performance of single leg drills on both legs.
Group II: HOMEExperimental Treatment1 Intervention
HOME Program is distinguished by patients participating in a home only intervention that consists of running and strengthening exercises performed twice a week for six weeks. No plyometric or agility drills are performed in this study arm. This represents the minimal intervention to prepare for a return to sports. No neuromuscular training or movement training beyond the sagittal plane will be performed.
Group III: STANActive Control1 Intervention
Patients in the STAN group will participate in twelve sessions of supervised physical therapy over a six week period. Patients will participate in agility and plyometric drills, and continue strength exercises from the previous treatment phase. The clinic program will be performed in conjunction with a home running program. Patients in this group will not receive feedback from the therapist regarding movement quality during activities.

Find a Location

Who is running the clinical trial?

Mayo ClinicLead Sponsor
3,191 Previous Clinical Trials
3,758,361 Total Patients Enrolled
1 Trials studying Rehabilitation
1 Patients Enrolled for Rehabilitation
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NIH
483 Previous Clinical Trials
1,086,789 Total Patients Enrolled
1 Trials studying Rehabilitation
250 Patients Enrolled for Rehabilitation
Nathaniel Bates, PhDPrincipal InvestigatorMayo Clinic
1 Previous Clinical Trials
196 Total Patients Enrolled

Media Library

Neuromuscular Intervention (Not Applicable) Clinical Trial Eligibility Overview. Trial Name: NCT03190889 — N/A
Rehabilitation Research Study Groups: STAN, HOME, TNMT
Rehabilitation Clinical Trial 2023: Neuromuscular Intervention Highlights & Side Effects. Trial Name: NCT03190889 — N/A
Neuromuscular Intervention (Not Applicable) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03190889 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the total number of individuals participating in this trial?

"The recruitment process requires 150 qualified candidates to be enlisted into this trial, and these participants can enter from Mayo Clinic in Florida (Jacksonville) and Mayo Clinic Square (Minneapolis)."

Answered by AI

To whom is enrollment in this research study accessible?

"In order to gain admittance into this study, participants must have received rehabilitation and be between the ages of 13-30. This research endeavour is looking to enrol approximately 150 people in total."

Answered by AI

Is this investigation accommodating those aged 50 and older?

"To qualify for this medical trial, patients must fall between the ages of 13 and 30. Conversely, there are 7 other studies specifically tailored towards minors as well as 57 clinical trials geared toward individuals 65 years or older."

Answered by AI

Is this experimental research being conducted in multiple locations within the city?

"Presently, there are 4 clinical sites signing up participants for this study - Mayo Clinic in Florida (Jacksonville), Mayo Clinic Square (Minneapolis) and the Rochester branch of Mayo Clinic."

Answered by AI

Are there still openings for participants in this clinical research initiative?

"This medical study, first posted on August 1st 2018 is currently searching for participants. The trial's information has been revised as recently as September 28th 2022 according to clinicaltrials.gov."

Answered by AI
~23 spots leftby Mar 2025