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Sedative

Combination of Dexmedetomidine with Midazolam for Preoperative Sedation

N/A

Waitlist Available

Research Sponsored by Nemours Children's Clinic

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up from beginning of when patient receives medication for assessing preoperative sedation to recovery room when postoperative delerium is assessed. this whole process takes approximately 90 minutes.

Awards & highlights

Study Summary

This trial is testing whether midazolam, dexmedetomidine, or a combination of the two drugs is the best premedication for children getting ear tube surgery. Children in the study will be randomly assigned to one of the three groups, and the group they are in will be unknown to the observers assessing sedation, mask acceptance, and postoperative delirium.

Eligible Conditions

Preoperative Sedation
Delirium
Mask Compliance

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ from beginning of when patient receives medication for assessing preoperative sedation to recovery room when postoperative delerium is assessed. this whole process takes approximately 90 minutes.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~from beginning of when patient receives medication for assessing preoperative sedation to recovery room when postoperative delerium is assessed. this whole process takes approximately 90 minutes.

This trial's timeline: 3 weeks for screening, Varies for treatment, and from beginning of when patient receives medication for assessing preoperative sedation to recovery room when postoperative delerium is assessed. this whole process takes approximately 90 minutes. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Post operative anesthesia emergence delerium scale

Trial Design

1Treatment groups

Experimental Treatment

Group I: Premedication with MidazolamExperimental Treatment1 Intervention

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Find a Location

Who is running the clinical trial?

Nemours Children's ClinicLead Sponsor

124 Previous Clinical Trials

18,131 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What medical symptoms can be addressed by a Dexmedetomidine plus Midazolam combination?

"The combination of dexmedetomidine and midazolam can be effectively deployed to combat anxiolysis, induce amnesia, and mitigate seizures."

Answered by AI

Is this investigation welcoming new participants?

"The clinical trial is not currently accepting patients, which was last updated on May 7th 2014. However, there are 165 other active trials in need of participants at this moment in time according to data provided by clinicaltrials.gov."

Answered by AI

Does this research accept participants who are beyond 35 years old?

"This medical trial seeks participants that are between the age of 6 months and 4 years."

Answered by AI

Am I qualified to partake in this research endeavor?

"To be accepted, participants must have had preoperative sedation and range in age from 6 Months to 4 years old. Approximately 60 individuals are being enrolled for this trial."

Answered by AI

What is the population size of participants in this investigation?

"As this study was last modified on May 7th 2014, it is not presently accepting new candidates. However, if you are interested in other trials, there are two studies recruiting for preoperative sedation and 163 investigations involving the combination of dexmedetomidine with midazolam currently looking to add participants."

Answered by AI

What findings have been revealed from combining Dexmedetomidine and Midazolam in previous experiments?

"Presently, 163 clinical trials are being conducted to analyse the efficacy of Combination of Dexmedetomidine with Midazolam. Of those studies, 30 have progressed to Phase 3 research experiments. While most locations carrying out these investigations are located in Porto Alegre, California, there exist 913 total sites studying this type of treatment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effect of Dexmedetomidine Versus Midazolam Versus a Combination of the Two as a Premedication for Children Undergoing Bilateral Myringotomy Tube Insertion

2014. "Effect of Dexmedetomidine Versus Midazolam Versus a Combination of the Two as a Premedication for Children Undergoing Bilateral Myringotomy Tube Insertion". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02134327.