← Back to Search

Procedure

Study Group for Total Knee Arthroplasty

N/A

Waitlist Available

Research Sponsored by Western University, Canada

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 days and at 3rd month

Awards & highlights

Study Summary

This trial is being done to compare the effectiveness of a combination of two pain-relief procedures (adductor canal block and I-PACK block) to a single pain-relief procedure (local infiltration analgesia) for people undergoing knee replacement surgery. The hypothesis is that the combination of the two procedures will result in less pain and a quicker hospital discharge.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3 days and at 3rd month

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3 days and at 3rd month

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 days and at 3rd month for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Time to achieve a collective four-point criterion for readiness to discharge from hospital after knee arthroplasty surgery.

Secondary outcome measures

Functional outcomes

Nausea and vomiting

Post-Operative pain scores

+5 more

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Study GroupActive Control1 Intervention

Spinal Anesthesia + ACB continuous catheter+ iPACK + Sham LIA

Group II: Comparator GroupPlacebo Group1 Intervention

Spinal Anesthesia + LIA + Sham Blocks

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

George Eliot Hospital NHS TrustOTHER

2 Previous Clinical Trials

4,730 Total Patients Enrolled

Western University, CanadaLead Sponsor

239 Previous Clinical Trials

56,951 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the age cap for this investigation set at 35 years of age or higher?

"In order to participate in this trial, volunteers must be between the ages of 18 and 70."

Answered by AI

Are there any criteria for participating in this clinical trial?

"This experimental research is open to 532 participants with total knee replacement surgery aged between 18 and 70. To be eligible, individuals must have a BMI of 18-40 and should be able to independently ambulate using only a standard wheeled walker as mobility equipment."

Answered by AI

Are participants still being accepted for this research endeavor?

"Unfortunately, this medical trial is currently at capacity and no longer accepting participants. The study was first posted on July 1st 2020 before the most recent update occurred on February 5th 2020. Nevertheless, there are 24 other clinical trials actively searching for patients right now."

Answered by AI

Recent research and studies

Acta OrthopaedicaJournal

Reduced Hospital Stay, Morphine Consumption, and Pain Intensity with Local Infiltration Analgesia After Unicompartmental Knee Arthroplasty

Essving, Per, Kjell Axelsson, Jill Kjellberg, Örjan Wallgren, Anil Gupta, and Anders Lundin. 2009. “Reduced Hospital Stay, Morphine Consumption, and Pain Intensity with Local Infiltration Analgesia After Unicompartmental Knee Arthroplasty”. Acta Orthopaedica. Medical Journals Sweden AB. doi:10.3109/17453670902930008.

Regional Anesthesia and Pain MedicineJournal

The Optimal Analgesic Block for Total Knee Arthroplasty

Bendtsen, Thomas Fichtner, Bernhard Moriggl, Vincent Chan, and Jens Børglum. 2016. “The Optimal Analgesic Block for Total Knee Arthroplasty”. Regional Anesthesia and Pain Medicine. BMJ. doi:10.1097/aap.0000000000000485.

Regional Anesthesia and Pain MedicineJournal

Adductor Canal Block Versus Femoral Nerve Block for Analgesia After Total Knee Arthroplasty

Jæger, Pia, Dusanka Zaric, Jonna S. Fomsgaard, Karen Lisa Hilsted, Jens Bjerregaard, Jens Gyrn, Ole Mathiesen, Tommy K. Larsen, and Jørgen B. Dahl. 2013. “Adductor Canal Block Versus Femoral Nerve Block for Analgesia After Total Knee Arthroplasty”. Regional Anesthesia and Pain Medicine. BMJ. doi:10.1097/aap.0000000000000015.

Anesthesia & AnalgesiaJournal