Study Summary
This trial will test whether an electronic video intervention and behavioral contract can help kidney transplant patients stick to their medication regimens.
Eligible Conditions
- Kidney Transplant
- Medication Adherence
Treatment Effectiveness
Effectiveness Progress
Study Objectives
2 Primary · 9 Secondary · Reporting Duration: study end (12 months after enrolment)
Month 12
Difference in adherence to immunosuppressant medications between intervention and control (immunosuppressant blood levels)
Difference in adherence to immunosuppressant medications between intervention and control (self-report)
Pharmaceutical Preparations
Difference in changes in kidney transplant knowledge between intervention and control
Difference in education satisfaction between intervention and control
Difference in quality of life between intervention and control
Difference in self efficacy between intervention and control
Month 12
Cost of administering the intervention
Days in hospital
Difference in adherence to transplant appointments between intervention and control
Video viewing habits (duration of viewing time)
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
Standard education
1 of 2
Video education + adherence contract
1 of 2
Active Control
Experimental Treatment
200 Total Participants · 2 Treatment Groups
Primary Treatment: Video education + adherence contract · No Placebo Group · N/A
Video education + adherence contract
Behavioral
Experimental Group · 1 Intervention: Video education + adherence contract · Intervention Types: BehavioralStandard educationNoIntervention Group · 1 Intervention: Standard education · Intervention Types:
Trial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: study end (12 months after enrolment)
Who is running the clinical trial?
University of Alberta Transplant Recipient ProgramUNKNOWN
Vancouver Coastal HealthOTHER_GOV
36 Previous Clinical Trials
11,808 Total Patients Enrolled
University of Illinois Health Sciences SystemUNKNOWN
Providence Health, St. Pauls Hospital - Renal Transplant ProgramUNKNOWN
American Society of Transplantation Research NetworkUNKNOWN
University of SaskatchewanLead Sponsor
237 Previous Clinical Trials
90,115 Total Patients Enrolled
Southern Alberta Transplant ProgramUNKNOWN
1 Previous Clinical Trials
162 Total Patients Enrolled
Saskatchewan Health Authority - Regina AreaOTHER
24 Previous Clinical Trials
3,748 Total Patients Enrolled
Eligibility Criteria
Age 18+ · All Participants · 3 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:I can speak, understand, and read English.
References
- Mansell, Holly, Nicola Rosaasen, Patricia West-Thielke, Jenny Wichart, Christopher Daley, Rahul Mainra, Ahmed Shoker, Juxin Liu, and David Blackburn. 2019. “Randomised Controlled Trial of a Video Intervention and Behaviour Contract to Improve Medication Adherence After Renal Transplantation: The VECTOR Study Protocol”. BMJ Open. BMJ. doi:10.1136/bmjopen-2018-025495.
- Mellon L, Doyle F, Hickey A, Ward KD, de Freitas DG, McCormick PA, O'Connell O, Conlon P. Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipients. Cochrane Database Syst Rev. 2022 Sep 12;9:CD012854. doi: 10.1002/14651858.CD012854.pub2. Review.
- Mellon L, Doyle F, Hickey A, Ward KD, de Freitas DG, McCormick PA, O'Connell O, Conlon P. Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipients. Cochrane Database Syst Rev. 2022 Sep 12;9(9):CD012854. doi: 10.1002/14651858.CD012854.pub2.
- Holly Mansell 2018. "Video Education and Behaviour Contract to Optimize Adherence in Renal Transplants". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03540121.
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Conditions
Cancer Related
Treatments