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Behavioral Intervention

Smoking Cessation for Smoking

N/A

Waitlist Available

Led By Archana Asundi, M.D.

Research Sponsored by Boston Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up week 12

Awards & highlights

Study Summary

This trial is testing how smoking affects the immune system in people with HIV infection.

Eligible Conditions

HIV/AIDS
Smoking

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ week 12

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~week 12

This trial's timeline: 3 weeks for screening, Varies for treatment, and week 12 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

.Difference in T cell and monocyte immune subsets, level of activation

Secondary outcome measures

Difference in levels of plasma inflammatory markers

Differences airway transcriptional profile

Differences in level of oxidative stress

+1 more

Trial Design

2Treatment groups

Experimental Treatment

Group I: SmokersExperimental Treatment5 Interventions

HIV-positive smokers will be enrolled in a smoking cessation program including the following procedures: Counseling Smoking cessation drugs Questionnaires Blood Draw Bronchoscopy

Group II: Non-SmokersExperimental Treatment3 Interventions

HIV-positive non-smokers will be enrolled as a comparison group to HIV-positive smokers and will have the following procedures: Questionnaires Blood Draw Bronchoscopy

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Counseling

2017

Completed Phase 4

~1970

Bronchoscopy

2002

Completed Phase 2

~2300

Blood Draw

2006

Completed Phase 4

~2400

Questionnaires

2013

Completed Phase 2

~3330

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

National Institute on Drug Abuse (NIDA)NIH

2,468 Previous Clinical Trials

2,619,296 Total Patients Enrolled

Boston Medical CenterLead Sponsor

383 Previous Clinical Trials

871,097 Total Patients Enrolled

Archana Asundi, M.D.Principal InvestigatorBoston Medical Center

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are individuals who are over 25 years of age eligible to participate in this trial?

"This study is only open to individuals 18 years and older, but younger than 75."

Answered by AI

Are there any openings for me to take part in this experiment?

"This clinical trial seeks 130 adult participants (aged between 18 and 75) who are habitually smoking. Prospective patients need to have a HIV infection, with an active antiretroviral therapy for at least 6 months; or be non-smokers certified by negative cotinine test results during the screening visit. Furthermore, they must possess haemoglobin levels of 8 g/dL or above, platelets count at 80 000/mm3 or higher as well as evidence of permanent sterility like hysterectomy and oophorectomy. Females of childbearing potential require certifying negative pregnancy tests (sensitive up to"

Answered by AI

Are new participants being accepted into this investigation?

"This specific clinical trial is not presently accepting participants, as per the information on clinicaltrials.gov. Despite this, there are 300 other studies that can still be accessed by potential patients; this project was initially posted in June 2017 and last updated April 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Impact of Smoking and Its Cessation on Systemic and Airway Immune Activation

2017. "Impact of Smoking and Its Cessation on Systemic and Airway Immune Activation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02836067.