← Back to Search

Pre-operative Antibiotics for Wound Infection

Phase 4
Waitlist Available
Led By Sumit Gupta, MD
Research Sponsored by Sumit Gupta
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up six weeks
Awards & highlights

Study Summary

This trial will test whether antibiotics improve outcomes for kids who've had percutaneous surgery for supracondylar humerus fractures. Eligible patients who consent will be followed for 3-6 weeks to see if they experience less pain, quicker healing, and fewer complications.

Eligible Conditions
  • Postoperative Wound Infection
  • Supracondylar Humerus Fractures

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~six weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and six weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Presence of Post-Operative Infection
Secondary outcome measures
Visual Analog Scale: Pain Score

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Pre-operative AntibioticsActive Control2 Interventions
Patients randomized to preoperative antibiotics will receive 25mg/kg cefazolin IV up to 1g or clindamycin 10mg/kg up to 600mg IV in cases of documented allergy to cefazolin.
Group II: Saline PlaceboPlacebo Group1 Intervention
Patients randomized to the no-antibiotic group will receive a saline placebo. This placebo will consist of a 10 mL pre-filled syringe of normal saline.

Find a Location

Who is running the clinical trial?

Sumit GuptaLead Sponsor
University of Missouri-ColumbiaOTHER
361 Previous Clinical Trials
627,826 Total Patients Enrolled
Sumit Gupta, MDPrincipal Investigator - University of Missouri-Columbia
University of Missouri Women's & Children's Hospital

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are applications to join this clinical experiment being accepted at the moment?

"Based on the information available via clinicaltrials.gov, this medical trial is recruiting participants right now. It was initially listed in August 2017 and its details were most recently updated at the start of December 2021."

Answered by AI

What is the aggregate size of participants in this experiment?

"Affirmative. Clinicaltrials.gov displays that this trial is actively recruiting patients, having initially been posted on August 18th 2017 and last edited December 1st 2021. The medical study aims to enroll 200 participants at a single location."

Answered by AI

What prior reports have there been regarding Pre-operative Antibiotics?

"Currently, there are 30 active trials for Pre-operative Antibiotics with 8 of these studies in the advanced Phase 3 stage. The majority of test sites are located around Chicago, though a total of 171 facilities across the United States are participating in research involving prophylactic antibiotics."

Answered by AI

What types of conditions can be managed with Pre-operative Antibiotics?

"Pre-operative Antibiotics are frequently used to reduce the incidence of post-surgical infection and can help with bacterial endocarditis, anaerobic bacteria infections, and other microbial ailments."

Answered by AI

To what extent can Pre-operative Antibiotics prove detrimental to individuals?

"The safety of Pre-operative Antibiotics was rated a 3, as it is has been approved by the relevant authorities and cleared through Phase 4 trials."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)
Sumit Gupta 2017. "Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03261830.
~22 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top