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Alpha-1 Blocker

Tamsulosin for Urinary Retention

Phase 4
Waitlist Available
Led By Majid Mirzazadeh, MD
Research Sponsored by Wake Forest University Health Sciences
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 30 days postoperatively
Awards & highlights

Study Summary

This trial is testing whether tamsulosin can prevent post-operative urinary retention in women undergoing same-day discharge pelvic reconstructive surgery.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 30 days postoperatively
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 30 days postoperatively for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of Participants With Postoperative (Day 0) Urinary Retention
Secondary outcome measures
Incidence of Delayed Urinary Retention
Number Emergency Department (ED) Visits
Patient Level of Satisfaction With Voiding Function
+2 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: TamsulosinExperimental Treatment1 Intervention
Patients in this arm will receive 10 days of 0.4 mg of oral tamsulosin once daily starting 5 days pre-operatively and continuing until all pills are completed.
Group II: PlaceboPlacebo Group1 Intervention
Patients in this arm will receive 10 days of identical-appearing placebo once daily starting 5 days pre-operatively and continuing until all pills are completed.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Tamsulosin
2002
Completed Phase 4
~16790

Find a Location

Who is running the clinical trial?

Wake Forest University Health SciencesLead Sponsor
1,239 Previous Clinical Trials
1,004,179 Total Patients Enrolled
2 Trials studying Urinary Retention
149 Patients Enrolled for Urinary Retention
Majid Mirzazadeh, MDPrincipal InvestigatorWake Forest Health Sciences
1 Previous Clinical Trials
100 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Obstetrics & GynecologyJournal
Committee Opinion No 701: Choosing the Route of Hysterectomy for Benign Disease
“Committee Opinion No 701: Choosing the Route of Hysterectomy for Benign Disease”. 2017. “Committee Opinion No 701: Choosing the Route of Hysterectomy for Benign Disease”. Obstetrics & Gynecology. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/aog.0000000000002112.
American Journal of Obstetrics and GynecologyJournal
Implementation of a Urogynecology-specific Enhanced Recovery After Surgery (ERAS) Pathway
Carter-Brooks, Charelle M., Angela L. Du, Kristine M. Ruppert, Anna L. Romanova, and Halina M. Zyczynski. 2018. “Implementation of a Urogynecology-specific Enhanced Recovery After Surgery (ERAS) Pathway”. American Journal of Obstetrics and Gynecology. Elsevier BV. doi:10.1016/j.ajog.2018.06.009.
Female Pelvic Medicine & Reconstructive SurgeryJournal
Duration of Catheterization After Retropubic Midurethral Sling
Geynisman-Tan, Julia, Bhumy Dave-Heliker, Katarzyna Bochenska, Sarah Collins, Christina Lewicky-Gaupp, Margaret Mueller, and Kimberly Kenton. 2018. “Duration of Catheterization After Retropubic Midurethral Sling”. Female Pelvic Medicine & Reconstructive Surgery. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/spv.0000000000000569.
International braz j urolJournal
Prophylactic Effects of Alpha-blockers, Tamsulosin and Alfuzosin, on Postoperative Urinary Retention in Male Patients Undergoing Urologic Surgery Under Spinal Anaesthesia
Akkoc, Ali, Cemil Aydin, Ramazan Topaktas, Mahir Kartalmis, Selcuk Altin, Kenan Isen, and Ahmet Metin. 2016. “Prophylactic Effects of Alpha-blockers, Tamsulosin and Alfuzosin, on Postoperative Urinary Retention in Male Patients Undergoing Urologic Surgery Under Spinal Anaesthesia”. International Braz J Urol. FapUNIFESP (SciELO). doi:10.1590/s1677-5538.ibju.2015.0256.
~1 spots leftby Apr 2025
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