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Local Anesthetic

Buffered Anesthetic for Toothache

Phase 4

Waitlist Available

Research Sponsored by Ying An, MD

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 10 minutes

Awards & highlights

Study Summary

This trial compares two types of local anesthesia in kids during dental injections while under deep sedation. One is plain, the other is buffered to reduce acidity and improve comfort.

Eligible Conditions

Toothache

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 10 minutes

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 10 minutes

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 10 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in CO2 level as measured by medical record

Change in blood pressure as measured by medical record

Change in heart rate as measured by as measured by medical record

+1 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Buffered AnestheticExperimental Treatment2 Interventions

Patients will be randomized to one side of the mouth getting the buffered anesthetic and the other side of the mouth to the non-buffered anesthetic.

Group II: Non-buffered AnestheticActive Control1 Intervention

Patients will be randomized to one side of the mouth getting the buffered anesthetic and the other side of the mouth to the non-buffered anesthetic.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Onset

2020

Completed Phase 4

~20

Buffered Anesthetic

2020

Completed Phase 4

~20

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Ying An, MDLead Sponsor

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research encompass geriatric patients?

"The youngest participants must be at least 2 years of age, and the oldest are capped at 6 for this trial."

Answered by AI

Has the Buffered Anesthetic received authorization from the FDA?

"The safety of Buffered Anesthetic received a score of 3 as it is currently in Phase 4, indicating that the therapeutic has been approved."

Answered by AI

Are there spaces still available for people to join this experiment?

"The clinical trial, which was initiated on December 8th 2020, is still actively recruiting per information from clinicaltrials.gov and the most recent update came through on February 23rd 2023."

Answered by AI

What is the current sample size of this clinical trial?

"Affirmative. Evidence on clinicaltrials.gov reveals that this medical investigation was initially uploaded on December 8th 2020 and is currently seeking participants. Specifically, 20 individuals are required from two separate sites for the study to be successful."

Answered by AI

To what demographic is this trial open?

"This research initiative is seeking 20 participants, aged between 2 and 6 years old with toothache. To be accepted into the trial they must meet those criteria."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Buffered Local Anesthetic

Ying An, MD 2020. "Buffered Local Anesthetic". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05757648.