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Exercise + Liraglutide for Metabolic Syndrome (ZQL008 Trial)
ZQL008 Trial Summary
This trial is studying whether exercise, liraglutide, or both can improve cardiac and skeletal muscle function in people with Metabolic Syndrome.
ZQL008 Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowZQL008 Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2017 Phase 4 trial • 100 Patients • NCT02014740ZQL008 Trial Design
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- I have diabetes or have taken medication for it.You have been regularly doing intense exercise for at least 20 minutes, two times a week.You have very high levels of triglycerides or cholesterol in your blood.I meet at least 3 of the 5 criteria for Metabolic Syndrome.You have health conditions that prevent you from participating in an exercise program.I am between 21 and 60 years old.Your "good" cholesterol (HDL) is too low.You are allergic to perflutren.Your triglyceride levels are higher than 150 mg/dl.My medication doses have been stable for at least 3 months.Your body mass index (BMI) is between 25 and 35, and you haven't gained or lost more than 5 kilograms in the past 6 months. This is to make it easier for doctors to check your heart and blood vessels.I have been on stable doses of certain heart or cholesterol medications for at least 3 months.Your blood sugar level when you haven't eaten is higher than 100 mg/dl.I am taking an ACE inhibitor or ARB medication.Your waist measurement is larger than 102 cm (for men) or 88 cm (for women).You have high blood pressure, with readings of 130mmHg or higher for systolic pressure, or 85mmHg or higher for diastolic pressure.Your body mass index (BMI) is between 25 and 35, and you have not gained or lost more than 5 kilograms in the past 6 months.I have previously used Liraglutide.I am between 21 and 60 years old.I am taking a beta blocker medication.I am currently smoking or quit smoking less than 5 years ago.Your blood pressure is higher than 160/90.I have a history of serious health issues, including heart, lung, liver, kidney diseases, or another cancer.
Frequently Asked Questions
Am I eligible to participate in this research?
"This research program is looking to enrol 80 individuals with metabolic syndrome between 21 and 60 years old. To qualify, they must have an increased waist circumference (≥102 cm in men; ≥88 cm in women), BMI >25 and ≤35 kg/m2, triglycerides at least 150 mg/dl, HDL-cholesterol under 40mg/dl for males or 50 mg/dl for females, systolic blood pressure of 130 mmHg or higher OR diastolic blood pressure 85mmHg+, fasting glucose levels greater than 100 mg/dL, and be on stable doses of ACE inhibitors and beta blockers for a"
Is the cutoff age for eligibility in this trial beyond eighty years?
"The qualifications for this study restrict applicants to those between 21 and 60 years old. By contrast, there are 388 trials available for minors, while 1070 exist for seniors."
Is this research experiment currently enrolling participants?
"Clinicaltrials.gov declares that this clinical trial is actively searching for participants, with the initial posting made on November 1st 2020 and most recently updated July 15th 2022."
What conditions does Liraglutide typically serve to ameliorate?
"Liraglutide is an effective therapeutic option for those suffering from exercise-induced symptoms, inadequate control on monotherapy treatments, and cardiovascular risk reduction."
How large is the population sample size for this research undertaking?
"Affirmative. Clinicaltrials.gov archives demonstrate that this trial, which was first publicized on November 1st 2020, is currently recruiting individuals for participation. 80 subjects are required to be enrolled from one medical centre."
Has the U.S. Food and Drug Administration given its stamp of approval to Liraglutide?
"There is ample evidence suggesting liraglutide's safety, thus it was given a score of 3 on our scale. This treatment has already been approved and released to the public in this Phase 4 trial."
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