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Local Anesthetic

Surgical wound infiltration for Surgical Wound Infiltration

Phase 4
Waitlist Available
Led By Hector Martinez-Wilson, MD
Research Sponsored by Duke University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up first seven days postoperatively
Awards & highlights

Study Summary

This trial is testing whether a Quadratus Lumborum (QL) plane injection technique, which numbs the nerves going to the abdominal area, is more effective than local anesthetic administered directly to the surgical incision in reducing post-operative pain.

Eligible Conditions
  • Surgical Wound Infiltration
  • Quadratus Lumborum Block

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~first seven days postoperatively
This trial's timeline: 3 weeks for screening, Varies for treatment, and first seven days postoperatively for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Opioid Consumption in Oral Morphine Milliequivalents for the First 24 Hours After Surgery (Defined as 24 Hours After the Anesthesia End Time)
Secondary outcome measures
Self-reported Ability to Walk for 15 Minutes Without Any Difficulty Within the First Postoperative Week
Self-reported Numeric Pain Scores on Postoperative Day Seven
Worst Bloating Severity in the First Postoperative Week

Trial Design

2Treatment groups
Active Control
Group I: Surgical wound infiltrationActive Control1 Intervention
Patients will receive 266 mg of liposomal bupivacaine mixed with 50 mg non-liposomal bupivacaine infiltrated into the wound by the surgeon.
Group II: Quadratus Lumborum (QL) BlockActive Control1 Intervention
Patients will receive a bilateral ultrasound guided QL block by the anesthesia team.

Find a Location

Who is running the clinical trial?

Duke UniversityLead Sponsor
2,358 Previous Clinical Trials
3,420,025 Total Patients Enrolled
Hector Martinez-Wilson, MDPrincipal InvestigatorDuke University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who has the capacity to partake in this medical experiment?

"This study is recruiting 40 individuals aged between 18 and 75 who have a surgical wound. Crucially, the ideal candidate must be able to speak English fluently, possess an ASA score of 1 or 2, and preparing for living donor nephrectomy."

Answered by AI

Are there any opportunities to enroll in this particular experiment?

"Yes, the information on clinicaltrials.gov confirms that this medical trial is ongoing and actively recruiting patients; it was first posted online at the end of January 2021 and has had its data edited most recently in mid-January 2022. The study requires 40 participants from a single site to be enrolled."

Answered by AI

Are there any health risks associated with Surgical wound infiltration?

"Surgical wound infiltration is judged to be safe with a rating of 3, as it has already been approved by the regulatory authorities after many phases of clinical trials."

Answered by AI

How many individuals are being administered treatment in this trial?

"Affirmative. The information housed on clinicaltrials.gov testifies that this experiment is currently recruiting participants, with 40 individuals sought from a single site since its posting date of January 25th 2021 and latest update of January 14th 2022."

Answered by AI

Is this research endeavor enrolling individuals over the age of eighty-five?

"As indicated in the study requirements, potential participants must be no younger than 18 years old and not older than 75."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Surgeon Infiltration QL Block Comparison
2021. "Surgeon Infiltration QL Block Comparison". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03496610.
~10 spots leftby Apr 2025
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