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Oxygen Therapy

Titration of nocturnal oxygen needs to prevent desaturations for Chronic Heart Failure (HO2F Trial)

Phase 4

Waitlist Available

Research Sponsored by Laval University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up three months ( titration completed 3 times during the study period)

Awards & highlights

HO2F Trial Summary

This trial is testing different levels of oxygen flow during sleep in order to minimize oxygen desaturation while also minimizing periods of hyperoxia.

Eligible Conditions

Chronic Heart Failure
Central Sleep Apnea

HO2F Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ three months ( titration completed 3 times during the study period)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~three months ( titration completed 3 times during the study period)

This trial's timeline: 3 weeks for screening, Varies for treatment, and three months ( titration completed 3 times during the study period) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Accuracy of automated oxygen titration

Changes in optimal levels of O2 flow ( EO2F) which prevent nocturnal O2 desaturation

HO2F Trial Design

1Treatment groups

Experimental Treatment

Group I: Oxygen therapyExperimental Treatment1 Intervention

Fixed nightime oxygen therapy throughout the protocol duration

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Who is running the clinical trial?

Laval UniversityLead Sponsor

417 Previous Clinical Trials

172,258 Total Patients Enrolled

OxynovUNKNOWN

Philips RespironicsIndustry Sponsor

66 Previous Clinical Trials

9,617 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the process of adjusting oxygen levels during sleep to avoid drops in saturation approved by the FDA?

"Titration of nocturnal oxygen needs to prevent desaturations is approved and has been given a rating of 3. This assessment was based on the fact that this procedure has passed Phase 4 clinical trials."

Answered by AI

Is enrollment for this research endeavor still available to participants?

"Estimations from clinicaltrials.gov establish that this investigation, which was initially posted on April 15th 2018, is recruiting participants currently. Its details were most recently modified on the 6th of April 2022."

Answered by AI

What is the current enrollment of participants in this clinical experimentation?

"Affirmative. According to the clinicaltrials.gov page, this study is actively recruiting participants who meet its requirements. The trial was first announced on April 15th 2018 and last updated on April 6th 2022; it will involve 14 patients from two separate medical centres."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Nocturnal Oxygen Needs and Central Sleep Apnea in Patients With Chronic Heart Failure.

Frédéric Sériès 2018. "Nocturnal Oxygen Needs and Central Sleep Apnea in Patients With Chronic Heart Failure.". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03254212.

All > Heart Failure With Preserved Ejection Fraction > Sleep Apnea