← Back to Search

Antifibrinolytic Agent

Epinephrine and Tranexamic Acid for Shoulder Impingement Syndrome

Phase 4
Waitlist Available
Led By Jason Old, MD, FRCSC
Research Sponsored by Panam Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day of surgery - post-operative day 14
Awards & highlights

Study Summary

This trial will study if an IV drug is an alternative to epinephrine for improving shoulder surgery visualization.

Eligible Conditions
  • Shoulder Impingement Syndrome
  • Rotator Cuff Tears
  • Subacromial Impingement Syndrome
  • Rotator Cuff Injury

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~intra-operative
This trial's timeline: 3 weeks for screening, Varies for treatment, and intra-operative for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Visualization Quality Scale
Secondary outcome measures
Pharmaceutical Preparations

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: Intravenous TXAExperimental Treatment1 Intervention
Tranexamic acid intervention used.
Group II: Epinephrine and TXAExperimental Treatment1 Intervention
Epinephrine and tranexamic acid intervention used.
Group III: Epinephrine in irrigation fluidActive Control1 Intervention
Epinephrine intervention used.
Group IV: No epinephrine or TXAActive Control1 Intervention
No intervention given.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Tranexamic acid
2018
Completed Phase 4
~42540
Epinephrine and Tranexamic Acid
2020
Completed Phase 4
~130

Find a Location

Who is running the clinical trial?

Panam ClinicLead Sponsor
16 Previous Clinical Trials
1,377 Total Patients Enrolled
1 Trials studying Shoulder Impingement Syndrome
86 Patients Enrolled for Shoulder Impingement Syndrome
University of ManitobaOTHER
595 Previous Clinical Trials
199,394 Total Patients Enrolled
Jason Old, MD, FRCSCPrincipal InvestigatorPan Am Clinic

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Acta OrthopaedicaJournal
Tranexamic Acid Reduces Blood Loss in Cemented Hip Arthroplasty: A Randomized, Double-blind Study of 39 Patients with Osteoarthritis
Niskanen, Raimo O, and Olli L Korkala. 2005. “Tranexamic Acid Reduces Blood Loss in Cemented Hip Arthroplasty: A Randomized, Double-blind Study of 39 Patients with Osteoarthritis”. Acta Orthopaedica. Medical Journals Sweden AB. doi:10.1080/17453670510045444.
The Journal of Bone and Joint Surgery. British volumeJournal
Systematic Review and Meta-analysis of the Use of Tranexamic Acid in Total Hip Replacement
Sukeik, M., S. Alshryda, F. S. Haddad, and J. M. Mason. 2011. “Systematic Review and Meta-analysis of the Use of Tranexamic Acid in Total Hip Replacement”. The Journal of Bone and Joint Surgery. British Volume. British Editorial Society of Bone & Joint Surgery. doi:10.1302/0301-620x.93b1.24984.
Journal of Surgical ResearchJournal
A Meta-analysis of the Effectiveness and Safety of Using Tranexamic Acid in Primary Unilateral Total Knee Arthroplasty
Tan, Jixiang, Hong Chen, Qin Liu, Cheng Chen, and Wei Huang. 2013. “A Meta-analysis of the Effectiveness and Safety of Using Tranexamic Acid in Primary Unilateral Total Knee Arthroplasty”. Journal of Surgical Research. Elsevier BV. doi:10.1016/j.jss.2013.03.099.
clinicaltrials.govStudy
Tranexamic Acid to Improve Arthroscopic Visualization in Shoulder Surgery
2020. "Tranexamic Acid to Improve Arthroscopic Visualization in Shoulder Surgery". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04594408.
~28 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top