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Treatment Group for Postoperative Pain

Phase 4
Waitlist Available
Led By Farzana Afroze, MD
Research Sponsored by Albany Medical College
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion 48 hours
Awards & highlights

Study Summary

This study hypothesizes that the addition of a low-dose ketamine infusion to usual post-operative pain management will improve pain control as evidenced by an improvement in post-operative pain scores for patients undergoing spinal fusion for idiopathic scoliosis.

Eligible Conditions
  • Idiopathic Scoliosis
  • Postoperative Pain

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion 48 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion 48 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Patient Satisfaction
Secondary outcome measures
Length of Stay
Opioid Use
Pain Score

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Treatment GroupExperimental Treatment1 Intervention
A ketamine bolus of 0.5mg/kg will be given and then the ketamine infusion of 0.2 mg/kg/hr will be initiated prior to incision. Intra-operative opioids will be at the discretion of the attending anesthesiologist. Postoperative management will include continuation of the study drug as well as a standardized morphine patient-controlled analgesia (PCA) and acetaminophen 15 mg/kg IV every 6 hours. On postoperative day 1, patients are started on ketorolac 0.5 mg/kg up to 15 mg IV q8h. On postoperative day 2 they are transitioned to ibuprofen 10 mg/kg up to 600 mg. The ketamine infusion will continue for 48 hours post operatively at which point the PCA is discontinued and patients are transitioned to oral pain medications (Roxicet or Lortab and Flexeril) as per the current protocol.
Group II: PlaceboPlacebo Group1 Intervention
A placebo (saline) will be given in place of ketamine
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ketamine
FDA approved

Find a Location

Who is running the clinical trial?

Albany Medical CollegeLead Sponsor
91 Previous Clinical Trials
11,447 Total Patients Enrolled
1 Trials studying Postoperative Pain
350 Patients Enrolled for Postoperative Pain
Farzana Afroze, MDPrincipal InvestigatorAlbany Medical College
1 Previous Clinical Trials
600 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Academic Emergency MedicineJournal
Reliability of the Visual Analog Scale for Measurement of Acute Pain
Bijur, Polly E., Wendy Silver, and E. John Gallagher. 2001. “Reliability of the Visual Analog Scale for Measurement of Acute Pain”. Academic Emergency Medicine. Wiley. doi:10.1111/j.1553-2712.2001.tb01132.x.
clinicaltrials.govStudy
Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis
Farzana Afroze 2013. "Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02651324.
All > Scoliosis
~4 spots leftby Apr 2025
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