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VG4 Gonio for Unequal Pupil Size

Phase 4

Waitlist Available

Research Sponsored by Prisma Health-Upstate

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 4 hours

Awards & highlights

Study Summary

This trial is being conducted to better understand when medical imaging is needed for patients with unequal pupil size. Participation includes 3 visits over the course of a week and taking various eye tests.

Eligible Conditions

Unequal Pupil Size
Anisocoria

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 4 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~4 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Number of Participants With Constricting Response to Pilocarpine 1% in the Pharmacologically Dilated Eye

Trial Design

1Treatment groups

Experimental Treatment

Group I: Eye Dilation and ConstrictionExperimental Treatment6 Interventions

Participants screened for hyperopia >+1 diopter using a phoropter, have their intraocular pressures measured using a tono pen, and have their iridocorneal angle measured with a gonio lens. Proparacaine hydrochloride 0.5% eye drops will be used to numb the eyes before measuring intraocular pressures and prior to gonio lens. The following day, the participant will receive one drop of tropicamide and one drop of 1% pilocarpine in the left eye. If the left eye has no response to the 1% pilocarpine, or if the diameter of the pupil returned to baseline size, we will ask participants to come back to the clinic on another day to have the process repeated in the right eye.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Tono pen AVIA

2022

Completed Phase 4

~20

Reichert phoropter

2022

Completed Phase 4

~20

Pilocarpine

FDA approved

Tropicamide

FDA approved

Proparacaine

FDA approved

VG4 Gonio

2022

Completed Phase 4

~20

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Prisma Health-UpstateLead Sponsor

82 Previous Clinical Trials

42,927 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many subjects are currently participating in this research endeavor?

"Affirmative. The information on clinicaltrials.gov confirms that this trial is currently recruiting patients, with the original posting having been made April 1st 2022 and the most recent update occurring April 21st 2022. This medical experiment requires 15 participants to be recruited from a single location."

Answered by AI

Are there any risks associated with VG4 Gonio use?

"The safety of VG4 Gonio was rated a 3 due to the successful completion of its Phase 4 trial, which enabled it's approval for use."

Answered by AI

Has recruitment commenced for this experiment?

"Affirmative. Clinicaltrials.gov's information confirms that this trial, which was posted on April 1st 2022, is presently open for enrollment. 15 volunteers are needed to be recruited from a single medical facility."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Wearing-Off Period of Pharmacological Dilation and Anisocoria

2022. "Wearing-Off Period of Pharmacological Dilation and Anisocoria". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05238233.