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Dexamethasone plus Radium-223 for Prostate Cancer (TRANCE Trial)
TRANCE Trial Summary
This trial is testing whether the addition of dexamethasone to radium-223 will help control PSA levels and reduce side effects during treatment in men with mCRPC.
TRANCE Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTRANCE Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.TRANCE Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
How many volunteers are involved in the current investigation?
"Absolutely. Per the information available on clinicaltrials.gov, this research is actively trying to acquire test subjects; initial postings were made on February 23rd 2018 and a recent update was done April 13th 2022. The requisite number of participants needed for this study is 24 from one single location."
Is the combination of Dexamethasone and Radium-223 a safe approach for patients?
"After assessing the safety of Dexamethasone plus Radium-223, our team at Power awarded it a score of 3 out of 3 as this drug is already approved."
What is the intended purpose of combining Dexamethasone and Radium-223 as a treatment?
"Ophthalmia, sympathetic ophthalmitis, eye inflammation and branch retinal vein occlusion can all be managed using a combination of Dexamethasone and Radium-223."
Is this medical experiment accepting new participants at the moment?
"Indeed, the clinicaltrials.gov page confirms that this medical trial is still open to applicants and was last revised on April 13th 2022. Initially posted in February 2018, it aims to recruit 24 patients from 1 site."
Are there any analogous studies that have combined Dexamethasone and Radium-223?
"Currently, 558 medical studies are being conducted to research the impact of Dexamethasone plus Radium-223. Of those studies, 144 reside in Phase 3 trials, with Mishawaka Indiana as their main base of operations. However, a total of 18710 locations worldwide are running clinical trials for this particular treatment."
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