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Nonsteroidal Anti-inflammatory Drug

Intervention with 162 mg aspirin for Prophylaxis of Preeclampsia

Phase 4
Waitlist Available
Research Sponsored by Methodist Medical Center of Illinois
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Any pregnant patient at Peoria FMC
Hx of pre-eclampsia
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, estimated 18 months
Awards & highlights

Study Summary

This is a study to assess if 162 mg of aspirin will decrease rates of preeclampsia in pregnant patients compared to 81 mg of aspirin.

Eligible Conditions
  • Prophylaxis of Preeclampsia

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, estimated 18 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, estimated 18 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of participants with eclampsia
Number of participants with preeclampsia
Secondary outcome measures
Number of participants with agranulocytosis
Number of participants with anaphylaxis
Number of participants with aplastic anemia
+2 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Intervention with 162 mg aspirinExperimental Treatment1 Intervention
Aspirin 162 mg daily for prevention of preeclampsia in pregnant patients at Family Medicine Clinic
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Acetylsalicylic acid
FDA approved

Find a Location

Who is running the clinical trial?

University of Illinois College of Medicine at PeoriaOTHER
14 Previous Clinical Trials
11,611 Total Patients Enrolled
UICOM Peoria Family Medicine ResidencyUNKNOWN
Methodist Medical Center of IllinoisLead Sponsor
2 Previous Clinical Trials
95 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Obstetrics & GynecologyJournal
ACOG Committee Opinion No. 743: Low-dose Aspirin Use During Pregnancy
“ACOG Committee Opinion No. 743: Low-dose Aspirin Use During Pregnancy”. 2018. “ACOG Committee Opinion No. 743: Low-dose Aspirin Use During Pregnancy”. Obstetrics & Gynecology. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/aog.0000000000002708.
New England Journal of MedicineJournal
Aspirin Versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia
Rolnik, Daniel L., David Wright, Liona C. Poon, Neil O’Gorman, Argyro Syngelaki, Catalina de Paco Matallana, Ranjit Akolekar, et al.. 2017. “Aspirin Versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia”. New England Journal of Medicine. Massachusetts Medical Society. doi:10.1056/nejmoa1704559.
American Journal of Obstetrics and GynecologyJournal
The Role of Aspirin Dose on the Prevention of Preeclampsia and Fetal Growth Restriction: Systematic Review and Meta-analysis
Roberge, Stéphanie, Kypros Nicolaides, Suzanne Demers, Jon Hyett, Nils Chaillet, and Emmanuel Bujold. 2017. “The Role of Aspirin Dose on the Prevention of Preeclampsia and Fetal Growth Restriction: Systematic Review and Meta-analysis”. American Journal of Obstetrics and Gynecology. Elsevier BV. doi:10.1016/j.ajog.2016.09.076.
American Journal of Obstetrics and GynecologyJournal
Optimal Aspirin Dosing for Preeclampsia Prevention
Seidler, Anna Lene, Lisa Askie, and Joel G. Ray. 2018. “Optimal Aspirin Dosing for Preeclampsia Prevention”. American Journal of Obstetrics and Gynecology. Elsevier BV. doi:10.1016/j.ajog.2018.03.018.
All > Preeclampsia > Durlaza
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