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Fosaprepitant for Postoperative Nausea

Phase 4
Waitlist Available
Led By Mark A Burbridge, MD
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Having a surgical procedure requiring general anesthesia, having a surgical procedure where neuromonitoing with somatosensory evoked potentials and motor evoked potentials neuromonitoring is requested by the surgical team
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline (pre-dose) and 30, 60, and 90 minutes post-dose
Awards & highlights

Study Summary

This trial will test if a medication given before surgery can interfere with nervous system monitoring during surgery.

Eligible Conditions
  • Postoperative Nausea

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline (pre-dose) and 30, 60, and 90 minutes post-dose
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline (pre-dose) and 30, 60, and 90 minutes post-dose for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Motor Evoked Potentials Amplitude (Left Upper Extremity)
Somatosensory Evoked Potentials (SEPs), Extremity Amplitude (Left Lower Extremity)
Somatosensory Evoked Potentials (SEPs), Extremity Amplitude (Left Upper Extremity)
+2 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: FosaprepitantExperimental Treatment1 Intervention
Patients included in this study will be administered fosaprepitant 150 mg IV.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Fosaprepitant 150 mg
2018
Completed Phase 4
~30

Find a Location

Who is running the clinical trial?

Stanford UniversityLead Sponsor
2,395 Previous Clinical Trials
17,341,609 Total Patients Enrolled
Mark A Burbridge, MDPrincipal InvestigatorStanford University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Effect of Fosaprepitant on Motor Evoked and Somatosensory Evoked Potentials Under General Anesthesia
Mark Burbridge 2018. "Effect of Fosaprepitant on Motor Evoked and Somatosensory Evoked Potentials Under General Anesthesia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03197064.
~2 spots leftby Apr 2025
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