← Back to Search

Opioid Analgesic

Tonsillectomy and Dilaudid + Tylenol for Postoperative Pain

Phase 4

Waitlist Available

Led By Samuel Pate, M.D.

Research Sponsored by University of Nebraska

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up preoperative weight compared to postoperative weight at 2-3 weeks after surgery

Awards & highlights

Study Summary

This trial will help doctors determine the best post-tonsillectomy pain medication regimen to minimize pain and help patients have a quicker recovery.

Eligible Conditions

Postoperative Pain
Postoperative Nausea and Vomiting
Postoperative Hemorrhage
Weight Changes

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ preoperative weight compared to postoperative weight at 2-3 weeks after surgery

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~preoperative weight compared to postoperative weight at 2-3 weeks after surgery

This trial's timeline: 3 weeks for screening, Varies for treatment, and preoperative weight compared to postoperative weight at 2-3 weeks after surgery for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Daily pain level

Secondary outcome measures

Daily nausea/vomiting

Daily oral liquid intake

Post tonsillectomy hemorrhage

+2 more

Trial Design

3Treatment groups

Active Control

Group I: Tonsillectomy and Dilaudid + TylenolActive Control2 Interventions

This represents patients who will be randomized (1:3 chance) to postoperative pain control with Dilaudid (hydromorphone) and Tylenol (Acetaminophen)

Group II: Tonsillectomy and PercocetActive Control1 Intervention

This represents patients who will be randomized (1:3 chance) to postoperative pain control with Percocet (Oxycodone and Acetaminophen)

Group III: Tonsillectomy and NorcoActive Control1 Intervention

This represents patients who will be randomized (1:3 chance) to postoperative pain control with Norco (Hydrocodone and Acetaminophen)

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of NebraskaLead Sponsor

539 Previous Clinical Trials

1,144,707 Total Patients Enrolled

Samuel Pate, M.D.Principal InvestigatorUniversity of Nebraska Medical Center Department of Otolaryngology - Head and Neck Surgery

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still vacancies for volunteers in this experiment?

"According to information on clinicaltrials.gov, this medical project is not currently open for recruitment as the most recent update was made in October 2017. However, there are a plethora of other studies that require participants at present."

Answered by AI

To what ailments is the combination of Tonsillectomy, Dilaudid and Tylenol commonly recommended?

"Tonsillectomy and the combination of Dilaudid with Tylenol are both effective treatments for ailments such as catarrh, rhinorrhoea, and musculoskeletal pain."

Answered by AI

Has there been any additional research conducted on the combination of Tonsillectomy and Dilaudid plus Tylenol?

"Currently, there are 114 clinical trials underway for Tonsillectomy and Dilaudid + Tylenol. Out of these active studies, 32 have entered phase 3. Although the majority take place in Boston, Massachusetts, 1033 locations throughout the nation offer this treatment option to patients."

Answered by AI

What is the uppermost capacity of patients allowed to join this medical experiment?

"This study has ceased patient search as of October 18th, 2017. If you are seeking other trials to take part in, 1087 studies related to postoperative hemorrhage and 114 involving Tonsillectomy and Dilaudid + Tylenol are presently recruiting patients."

Answered by AI

Has the FDA authorized Tonsillectomy and Dilaudid + Tylenol for use?

"Our team at Power assigned a 3 out of 3 rating to the safety profile for Tonsillectomy and Dilaudid + Tylenol, as this is an approved Phase 4 trial."

Answered by AI

Recent research and studies

Otolaryngology–Head and Neck SurgeryJournal

A Comparison of Postoperative Pain and Complications in Tonsillectomy Using Biclamp Forceps and Electrocautery Tonsillectomy

Lee, Seung Won, Soo Sung Jeon, Jong Dae Lee, Jae Yong Lee, Shi Chan Kim, and Yoon Woo Koh. 2008. “A Comparison of Postoperative Pain and Complications in Tonsillectomy Using Biclamp Forceps and Electrocautery Tonsillectomy”. Otolaryngology–head and Neck Surgery. SAGE Publications. doi:10.1016/j.otohns.2008.04.004.

Otolaryngology–Head and Neck SurgeryJournal

Comparison of Posttonsillectomy Pain Using the Ultrasonic Scalpel, Coblator, and Electrocautery

Parsons, Stephen P., Susan R. Cordes, and Brett Comer. 2006. “Comparison of Posttonsillectomy Pain Using the Ultrasonic Scalpel, Coblator, and Electrocautery”. Otolaryngology–head and Neck Surgery. SAGE Publications. doi:10.1016/j.otohns.2005.09.027.

The LaryngoscopeJournal

Coblation Versus Unipolar Electrocautery Tonsillectomy: A Prospective, Randomized, Single-blind Study in Adult Patients

Noordzij, J Pieter, and Brian D. Affleck. 2006. “Coblation Versus Unipolar Electrocautery Tonsillectomy: A Prospective, Randomized, Single-blind Study in Adult Patients”. The Laryngoscope. Wiley. doi:10.1097/01.mlg.0000225944.00189.e9.

Clinical OtolaryngologyJournal