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Coronary Intervention
Coronary Intervention for Atherosclerotic Plaque (PREVENT Trial)
Phase 4
Waitlist Available
Led By Duk-woo Park, MD
Research Sponsored by Seung-Jung Park
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights
PREVENT Trial Summary
This trial will compare how well two different treatments work in preventing heart attacks, death, or the need for a repeat procedure. One treatment is a coronary intervention (a stent or similar treatment) plus optimal medical therapy. The other treatment is optimal medical therapy alone.
Eligible Conditions
- Coronary Artery Disease
- Atherosclerotic Plaque
PREVENT Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 2 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Target vessel failure
Secondary outcome measures
Any hospitalization for cardiac or noncardiac causes
Composite of any death, myocardial infarction, or repeat revascularization
Death from all, cardiac, or noncardiac causes
+14 morePREVENT Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Coronary interventionExperimental Treatment1 Intervention
bioabsorbable vascular scaffolds (BVS) (early period) or everolimus-eluting stents (middle and late period) +Optimal Medical Treatment
Group II: Optimal Medical TreatmentActive Control1 Intervention
Optimal Medical Treatment
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Coronary intervention
2015
Completed Phase 4
~1610
Find a Location
Who is running the clinical trial?
CardioVascular Research Foundation, KoreaOTHER
106 Previous Clinical Trials
221,716 Total Patients Enrolled
66 Trials studying Coronary Artery Disease
181,433 Patients Enrolled for Coronary Artery Disease
Seung-Jung ParkLead Sponsor
80 Previous Clinical Trials
238,699 Total Patients Enrolled
55 Trials studying Coronary Artery Disease
219,961 Patients Enrolled for Coronary Artery Disease
Duk-woo Park, MDPrincipal InvestigatorAsan Medical Center
4 Previous Clinical Trials
5,682 Total Patients Enrolled
3 Trials studying Coronary Artery Disease
3,674 Patients Enrolled for Coronary Artery Disease
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You have had stents placed in your body.You have lesions in your bypass graft.You have three or more specific areas of concern in your body.You have two problem areas in the same part of your heart.You have very calcified or sharply angled lesions.You have a specific type of heart artery blockage that requires two stents to be placed.You need to have a surgery called CABG for your heart condition.You cannot take or plan to stop taking two types of medicine that prevent blood clots within the next year.You have a blockage in a blood vessel that is more than half closed, but the blood flow through the blockage is still good, and you meet certain criteria related to the size of the blockage, the amount of plaque, and the type of plaque.You can have a certain type of heart procedure using a specific kind of stent.The blood vessel being treated is a specific size, between 2.75 and 4.0.The length of the lesion is less than or equal to 40 millimeters.You are not expected to live for more than 2 years.You are scheduled for a major surgery on your heart or another part of your body.You are 18 years old or older.You are being tested for or have known heart artery disease and are having a procedure to check your heart.
Research Study Groups:
This trial has the following groups:- Group 1: Coronary intervention
- Group 2: Optimal Medical Treatment
Awards:
This trial has 3 awards, including:- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Drug Has Already Been Approved - The FDA has already approved this drug, and is just seeking more data.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are there any available spots to join this medical experiment?
"According to the information found on clinicaltrials.gov, this trial is no longer enrolling participants. Originally posted in October 2015 with its last update taking place in November 2021, 760 other studies are actively recruiting patients at present."
Answered by AI
Is Coronary intervention a safe medical procedure for patients to undergo?
"The safety rating of coronary intervention is a 3, signifying that this treatment has been approved after multiple phases of clinical trials."
Answered by AI
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