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Celecoxib for Postoperative Pain
Study Summary
This trial will compare the effects of two different drugs on post-operative pain after impacted third molar surgery.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have a history of heart or stroke-related issues.I have liver disease or a condition affecting my liver.I am in good or mild systemic disease state according to ASA.You are allergic to common pain relievers like NSAIDs, aspirin, acetaminophen, or sulfa drugs.I am planning to have at least one wisdom tooth removed.I have severe gum infection around my wisdom tooth that needs removal.You have a severe health condition classified as ASA 3 or higher.
- Group 1: Celecoxib plus Placebo
- Group 2: Celecoxib plus Acetaminophen
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Drug Has Already Been Approved - The FDA has already approved this drug, and is just seeking more data.
- Approved for 10 Other Conditions - This treatment demonstrated efficacy for 10 other conditions.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Who meets the prerequisites to be involved in this clinical experiment?
"This medical trial is searching for around 100 candidates who suffer from postoperative pain and are between 18 to 45 years old."
Are there any vacancies open to prospective participants in this experiment?
"Affirmative. Clinicaltrials.gov records prove that this research project, initially advertised on April 22nd 2021, is still open for applicants. The investigators are aiming to enrol 100 subjects from 2 separate clinical centres."
What purpose is the combination of Celecoxib and Acetaminophen commonly used to serve?
"Celecoxib combined with Acetaminophen is regularly prescribed as a remedy for catarrh, but can also be employed to alleviate rhinorrhoea, musculoskeletal pain, and muscle cramping."
Is the combination of Celecoxib and Acetaminophen considered safe for human use?
"There is a wealth of evidence and approval from the medical community for Celecoxib plus Acetaminophen, thus it was given a rating of 3 out of 3."
How many study participants are enrolled in this research endeavor?
"Affirmative. The records located on clinicaltrials.gov demonstrate that this medical investigation began recruitment in April 2021 and was recently updated in November 2022. At present, the study is looking to recruit 100 participants from two distinct sites."
Is this trial open to individuals who have reached the legal age of majority?
"As per the study's inclusionary requirements, participants must be between 18 and 45 years of age."
Have researchers conducted any investigations into the combined use of Celecoxib and Acetaminophen?
"At present, 126 studies exploring Celecoxib plus Acetaminophen are underway. 31 of these experiments have entered Phase 3 and can be located at 2169 sites across the United States, with the majority being centered in Winston-Salem, North carolina."
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