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Analgesic

Acetaminophen 650 mg Oral Tablet for Postoperative Pain

Phase 4
Waitlist Available
Led By David Seel, DO.
Research Sponsored by William Beaumont Hospitals
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 7 days
Awards & highlights

Study Summary

This trial will test whether taking acetaminophen regularly instead of as-needed reduces post-operative pain and opiate use.

Eligible Conditions
  • Postoperative Pain
  • Sinus Surgery

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~7 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 7 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of Doses of Opiate (Narcotic) Pain Medication
Secondary outcome measures
Chronic Use of Pain Medication
Highest Subjective Pain Score
Lowest Subjective Pain Score
+5 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Study ArmExperimental Treatment2 Interventions
Acetaminophen 650 mg 1 tab every 6 hours round the clock plus Oxycodone 5 mg 1 tab every 6 hours as needed for breakthrough pain,.
Group II: Standard of Care armActive Control2 Interventions
Standard of Care Post-operative pain medication, Acetaminophen 325 mg every 6 hours as needed for pain plus acetaminophen/hydrocodone 7.5 mg/325 mg 1 tab every 4 hours as needed for pain.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Acetaminophen
FDA approved
Acetaminophen
FDA approved

Find a Location

Who is running the clinical trial?

William Beaumont HospitalsLead Sponsor
149 Previous Clinical Trials
112,793 Total Patients Enrolled
David Seel, DO.4.214 ReviewsPrincipal Investigator - William Beaumont Hospital - Farmington Hills
William Beaumont Hospitals
1Patient Review
Dr. Seel preformed 2 sets of tubes, the second set included a adenoidectomy and he said that he was being “conservative” and didn’t want to remove his tonsils. My sons issues continued and he ended up recommending a tonsillectomy less than a year later. So we now having to put my son under anesthesia again less than a year later because his tonsils did need to be removed. Which makes us feel like he was setting himself up for yet another surgery rather than being truly conservative in his initial approach.

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~12 spots leftby Apr 2025