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Lithium Carbonate for Osteosarcoma (Li2CO3 Trial)

Phase 4
Waitlist Available
Led By Jin Wang, PhD
Research Sponsored by Sun Yat-sen University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at least 24 months or at most 120 months
Awards & highlights

Li2CO3 Trial Summary

The purpose of this study is to determine whether Lithium Carbonate combined with neo-adjuvant chemotherapy improve the prognosis of osteosarcoma

Li2CO3 Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at least 24 months or at most 120 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and at least 24 months or at most 120 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
progression-free survival,incidence of chemotherapy-induced myelosuppression
Secondary outcome measures
over-all survival,metastasis-free survival

Li2CO3 Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Lithium CarbonateExperimental Treatment1 Intervention
Patients in this arm take Lithium Carbonate twice a day with a dose of 20-25mg/kg/d.
Group II: PlaceboPlacebo Group1 Intervention
The shape,color and smell of placebo are similar to Lithium Carbonate tablet used in the treatment arm.Patients in this arm take placebo twice a day.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Lithium carbonate
FDA approved

Find a Location

Who is running the clinical trial?

Nanfang Hospital of Southern Medical UniversityOTHER
435 Previous Clinical Trials
732,599 Total Patients Enrolled
Sun Yat-sen UniversityLead Sponsor
1,525 Previous Clinical Trials
3,450,160 Total Patients Enrolled
2 Trials studying Osteosarcoma
122 Patients Enrolled for Osteosarcoma
Qilu Hospital of Shandong UniversityOTHER
348 Previous Clinical Trials
802,521 Total Patients Enrolled
1 Trials studying Osteosarcoma
148 Patients Enrolled for Osteosarcoma

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Expert Opinion on Emerging DrugsJournal
An Update on Emerging Drugs in Osteosarcoma: Towards Tailored Therapies?
Hattinger, Claudia Maria, Maria Pia Patrizio, Federica Magagnoli, Silvia Luppi, and Massimo Serra. 2019. “An Update on Emerging Drugs in Osteosarcoma: Towards Tailored Therapies?”. Expert Opinion on Emerging Drugs. Informa UK Limited. doi:10.1080/14728214.2019.1654455.
clinicaltrials.govStudy
Clinical Trial of Lithium Carbonate Combined With Neo-adjuvant Chemotherapy to Treat Osteosarcoma
Jin Wang 2013. "Clinical Trial of Lithium Carbonate Combined With Neo-adjuvant Chemotherapy to Treat Osteosarcoma". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01669369.
~32 spots leftby May 2025
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