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Opioid Agonist

Rapid initiation for Opioid Use Disorder (RIDE Trial)

Phase 4
Waitlist Available
Research Sponsored by University of Pennsylvania
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months
Awards & highlights

RIDE Trial Summary

This trialwill test a mobile, rapid induction procedure to engage individuals in ongoing medication-assisted treatment for opioid use disorder.

Eligible Conditions
  • Opioid Use Disorder
  • Overdose

RIDE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Enrollment in Medication Assisted Treatment at 1-month Post-enrollment
Secondary outcome measures
Change in Opioid Use From Baseline to 6-month Follow-up
Economic Value of the Mobile Intervention Relative to Treatment as Usual
Enrollment in Medication Assisted Treatment at 6-month Post-enrollment
+1 more

Side effects data

From 2007 Phase 4 trial • 60 Patients • NCT00684073
8%
Fatigue
6%
Headache
6%
Hyperhidrosis
100%
80%
60%
40%
20%
0%
Study treatment Arm
Subutex®/Suboxone®

RIDE Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Rapid initiationExperimental Treatment1 Intervention
Rapid initiation of buprenorphine/naloxone, counseling, peer support and case management
Group II: Treatment as usualActive Control1 Intervention
Seeking treatment from the BAC/CRC (treatment as usual)
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
buprenorphine/naloxone
2017
Completed Phase 4
~890

Find a Location

Who is running the clinical trial?

Philadelphia Department of Public HealthFED
4 Previous Clinical Trials
1,244,637 Total Patients Enrolled
Public Health Management CorporationOTHER
16 Previous Clinical Trials
5,230 Total Patients Enrolled
University of PennsylvaniaLead Sponsor
2,002 Previous Clinical Trials
42,880,895 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Rapid Initiation of Drug Treatment Engagement
2019. "Rapid Initiation of Drug Treatment Engagement". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03908437.
~18 spots leftby Apr 2025
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