Your session is about to expire
← Back to Search
Dexamethasone 4 mg/ml for Neuropathy
Phase 4
Waitlist Available
Led By Akhil Chhatre, MD
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
patients with a diagnosis of either cervical, thoracic, or lumbar facet or sacroiliac joint pain who have responded to medial branch blocks and are already scheduled for bilateral radiofrequency ablations
age greater than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 4 weeks
Awards & highlights
Study Summary
This trial is testing whether dexamethasone, injected at the time of the procedure, can prevent post-ablation neuritis (nerve pain) better than a placebo.
Eligible Conditions
- Radioiodine Ablation
- Neuropathy
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 4 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~4 weeks
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Number of Lesions With Post-Ablation Neuritis
Side effects data
From 2013 Phase 4 trial • 122 Patients • NCT014749152%
Deep Vein Thrombosis
2%
Cerebrospinal fluid leak
2%
Fever
100%
80%
60%
40%
20%
0%
Study treatment Arm
Ondansetron
Aprepitant
Trial Design
2Treatment groups
Experimental Treatment
Placebo Group
Group I: DexamethasoneExperimental Treatment1 Intervention
Lesions where dexamethasone 4 milligram is administered post-radiofrequency ablation
Group II: PlaceboPlacebo Group1 Intervention
Lesions where 1 milliliter of normal saline is administered post-radiofrequency ablation
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Dexamethasone
FDA approved
Find a Location
Who is running the clinical trial?
Johns Hopkins UniversityLead Sponsor
2,256 Previous Clinical Trials
14,820,008 Total Patients Enrolled
Akhil Chhatre, MDPrincipal InvestigatorJohns Hopkins University
1 Previous Clinical Trials
100 Total Patients Enrolled
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Share this study with friends
Copy Link
Messenger