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Opioid Analgesic

Hydrocodone 5mg/acetaminophen 325mg for Nail Diseases

Phase 4

Waitlist Available

Led By Shari Lipner, MD, PhD

Research Sponsored by Weill Medical College of Cornell University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 days, 6 days (end of study)

Awards & highlights

Study Summary

This trial will compare the effectiveness of two different pain-relief drug combinations for people undergoing nail procedures.

Eligible Conditions

Nail Diseases
Nail Abnormalities

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3 days, 6 days (end of study)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3 days, 6 days (end of study)

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 days, 6 days (end of study) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change From Baseline in Pain Scores on Postoperative Day 2, as Measured by the Wong-Baker 0-to-10 Pain Scale

Secondary outcome measures

Change in Health-related Quality of Life Scores on Postoperative Days 3 and 6, as Measured by an Adapted APS-POQ-R Questionnaire

Trial Design

2Treatment groups

Active Control

Group I: Hydrocodone 5mg/acetaminophen 325mgActive Control3 Interventions

Participants receive oral hydrocodone 5 mg/acetaminophen 325 mg every 4 hours for 2 days, followed by oral acetaminophen 1000 mg and oral ibuprofen 400 mg every 6 hours for 4 days

Group II: Acetaminophen 1000mg + Ibuprofen 400mgActive Control2 Interventions

Participants receive oral acetaminophen 1000 mg and oral ibuprofen 400 mg every 6 hours for 6 days

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Weill Medical College of Cornell UniversityLead Sponsor

1,055 Previous Clinical Trials

1,316,309 Total Patients Enrolled

4 Trials studying Nail Diseases

21 Patients Enrolled for Nail Diseases

Shari Lipner, MD, PhDPrincipal InvestigatorWeill Medical College of Cornell University

3 Previous Clinical Trials

73 Total Patients Enrolled

1 Trials studying Nail Diseases

11 Patients Enrolled for Nail Diseases

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can individuals aged over 40 partake in this experiment?

"To adhere to the inclusion criteria of this medical trial, patient must be 18 years or older and no more than 95."

Answered by AI

Has the Food and Drug Administration authorized Hydrocodone 5mg/acetaminophen 325mg?

"Due to it being a Phase 4 trial, Hydrocodone 5mg/acetaminophen 325mg has been granted a security rating of 3 - indicating that the medication is approved for use."

Answered by AI

Is enrollment for this clinical trial still available?

"As of October 11th 2022, this study is no longer enrolling patients. This trial initially appeared on clinicaltrials.gov November 1st 2022 but has since concluded its recruitment efforts and ended the search for participants. Fortunately, 6 other active trials are currently recruiting volunteers in related fields."

Answered by AI

Can I register for this clinical experiment?

"This research study is currently recruiting 20 participants with nail conditions, aged 18 to 95. In order for applicants to be considered, they must fulfill the following criteria: undergoing fingernail or toenail excision/shave biopsy; both male and female are eligible; comprehension of voluntary informed consent forms; adherence to visit schedules and other protocol requirements."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Hydrocodone Compared to Acetaminophen and Ibuprofen for Post-nail Procedure Analgesia

2022. "Hydrocodone Compared to Acetaminophen and Ibuprofen for Post-nail Procedure Analgesia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05544734.