Wavefront-guided vs. Optimized LASIK for Myopia

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: Stanford University

Disqualifiers: Thin corneas, Keratoconus, Autoimmune, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

100 Participants Needed

Trial Summary

What is the purpose of this trial?

The investigators are comparing outcomes of LASIK surgery using a high definition wavefront-guided laser to a wavefront-optimized laser in patients with nearsightedness with and without astigmatism.

Research Team

Edward E. Manche, MD

Principal Investigator

Stanford University

Eligibility Criteria

This trial is for adults over 21 with healthy eyes who have nearsightedness ranging from very mild to severe (-0.25 to -11.00 diopters), with or without astigmatism up to 5.00 diopters. It's not suitable for those with certain eye conditions like keratoconus, pregnant or nursing individuals, people under 21, those with thin corneas, significant differences in vision between eyes, or autoimmune diseases.

Inclusion Criteria

Nearsightedness between -0.25 diopters and -11.00 diopters with or without astigmatism of up to 5.00 diopters

I am 21 or older with healthy eyes.

Exclusion Criteria

I am under 21 years old.

My corneas are very thin.

Patients with more than 1.5 diopter difference in astigmatism between eyes

Treatment Details

Interventions

• High Resolution Wavefront-guided LASIK
• Wavefront Optimized LASIK

Trial Overview The study is examining the effectiveness of two types of LASIK surgery: one using a high definition wavefront-guided laser and the other using a wavefront-optimized laser. The goal is to see which method provides better results for correcting nearsightedness and astigmatism.

Participant Groups

Group I: iDesign WFG LASIK Active Control 1 Intervention

Wavefront-guided LASIK

Group II: Wavelight WFO LASIK Active Control 1 Intervention

Wavefront-optimized LASIK

Who Is Running the Clinical Trial?

Stanford University

Lead Sponsor

Trials

2,527

Recruited

17,430,000+