High dose statin for Mitochondrial Disease

"Correct. According to information posted on clinicaltrials.gov, this experimental trial is actively seeking cohorts and was initially published on February 22nd 2018. The study needs 66 individuals from 2 separate locations for successful completion."

"The research into high dose statin began at OHSU Hospital in 2005 and has since completed 633 trials. Presently, 70 investigations are ongoing with Greenville, North carolina being a major source of these studies."

"Based on the criteria set forth by this particular medical trial, the participants must be between 35 and 65 years of age. Those younger than 18 or older than sixty-five will find fourteen trials specially designed for them while there are seventy-five options that accommodate those over the age of sixty-five."

"This medical trail is searching for 66 individuals with mitochondrial diseases, between the ages of 35 and 65. Most importantly, applicants must meet a specific BMI range (25-43), maintain weight stability within 5% in the prior 3 months, as well as abstain from consuming Nonsteroidal Antiinflammatory Drugs (NSAIDs) or aspirin 7 days before muscle biopsy."

"Presently, there are 70 active studies related to high dose statin being conducted at 162 cities in 28 countries. The first trial of this kind was held by Merck Sharp & Dohme LLC and completed its final drug approval phase back in 2005 with 80 participants. Since then, 633 further clinical trials have been successfully finished and documented."

"High dose statin therapy can be effective in mitigating the symptoms of lipidemias, postoperative thromboembolism, and anginal pain."

"Data confirms that high dose statin is safe and approved, resulting in an overall score of 3."

"Correct. Information posted on clinicaltrials.gov confirms that recruitment for this research is ongoing, having been initially published February 22nd 2018 and last updated May 2nd 2022. A total of 66 participants are needed to be recruited from two medical facilities."