Oxandrolone for Torn Knee Ligaments
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you must stop all current medications, but you cannot participate if you are taking medications that interfere with testosterone production or function, such as 5α-reductase inhibitors or certain cholesterol-lowering drugs.
What is the purpose of this trial?
This study is about healing after a rmultiligament knee reconstruction procedure. We hope to learn if a biologic medication: Oxandrolone, a synthetic derivative of the human hormone Testosterone (the principal male sex hormone and an anabolic steroid), given for 12 weeks is effective in aiding in the healing process and restoring muscle mass.
Research Team
George Hatch, MD
Principal Investigator
University of Southern California
Eligibility Criteria
This trial is for individuals with MRI-confirmed multiple ligament injuries in the knee who are scheduled for reconstruction surgery. It's designed to see if taking Oxandrolone, a synthetic hormone, helps heal and rebuild muscle after surgery.Inclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive Oxandrolone or placebo for 12 weeks to aid in healing and muscle mass restoration
Follow-up
Participants are monitored for changes in lean body mass and body fat percentage
Treatment Details
Interventions
- Oxandrolone
Find a Clinic Near You
Who Is Running the Clinical Trial?
George F. Hatch
Lead Sponsor