Oxandrolone for Torn Knee Ligaments
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether Oxandrolone, a medication related to testosterone, improves healing of knee injuries after major surgery that repairs multiple torn ligaments. Researchers aim to determine if it can restore muscle mass and accelerate recovery. Participants will receive either Oxandrolone or a placebo (a non-active treatment) for 12 weeks. This trial suits individuals with MRI-confirmed multiple knee ligament injuries who are scheduled for reconstruction surgery. As a Phase 4 trial, Oxandrolone is already FDA-approved and proven effective, and this research seeks to understand its benefits for more patients.
Will I have to stop taking my current medications?
The trial does not specify if you must stop all current medications, but you cannot participate if you are taking medications that interfere with testosterone production or function, such as 5α-reductase inhibitors or certain cholesterol-lowering drugs.
What is the safety track record for Oxandrolone?
Research has shown that Oxandrolone, a synthetic form of testosterone, is generally safe for use. Studies have found that drugs like Oxandrolone can aid recovery after surgeries, such as ligament repairs or joint replacements. The FDA has approved Oxandrolone for other uses, indicating its general safety.
Evidence suggests it can be used safely for several weeks. For instance, a study on an Oxandrolone implant under the skin found it was safe and well-tolerated for 24 weeks. This indicates that using Oxandrolone after knee surgery might not pose major safety concerns.
Consult a healthcare professional about potential risks and benefits before deciding to join a clinical trial.12345Why are researchers enthusiastic about this study treatment?
Unlike standard treatments for torn knee ligaments, which often include surgery or physical therapy, Oxandrolone offers a novel approach by promoting muscle growth and tissue repair through its anabolic steroid properties. This treatment is unique because it works by enhancing protein synthesis, potentially speeding up recovery and strengthening the knee more effectively than traditional methods. Researchers are excited about Oxandrolone's potential to reduce recovery time significantly and improve outcomes for patients with torn knee ligaments.
What is the effectiveness track record for Oxandrolone in aiding healing after multiligament knee reconstruction?
Research has shown that oxandrolone, a type of anabolic steroid, can prevent muscle loss and promote muscle growth. One study found that just two weeks of oxandrolone use reduced muscle shrinking and increased muscle size. Anabolic steroids like oxandrolone have also helped people recover better after knee surgeries and joint replacements. In this trial, participants in the treatment group will receive oxandrolone to study its potential to aid healing after knee ligament surgeries.12567
Who Is on the Research Team?
George Hatch, MD
Principal Investigator
University of Southern California
Are You a Good Fit for This Trial?
This trial is for individuals with MRI-confirmed multiple ligament injuries in the knee who are scheduled for reconstruction surgery. It's designed to see if taking Oxandrolone, a synthetic hormone, helps heal and rebuild muscle after surgery.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive Oxandrolone or placebo for 12 weeks to aid in healing and muscle mass restoration
Follow-up
Participants are monitored for changes in lean body mass and body fat percentage
What Are the Treatments Tested in This Trial?
Interventions
- Oxandrolone
Find a Clinic Near You
Who Is Running the Clinical Trial?
George F. Hatch
Lead Sponsor