← Back to Search

Oxandrolone for Torn Knee Ligaments

Phase 4

Recruiting

Led By George Hatch, MD

Research Sponsored by George F. Hatch

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

• Patients with MRI proven multiligament knee injury scheduled to undergo multiligament knee reconstruction

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up change from baseline at 52 weeks

Awards & highlights

Study Summary

This trial looks at using a steroid to help with healing & restoring muscle after a knee reconstruction.

Who is the study for?

This trial is for individuals with MRI-confirmed multiple ligament injuries in the knee who are scheduled for reconstruction surgery. It's designed to see if taking Oxandrolone, a synthetic hormone, helps heal and rebuild muscle after surgery.Check my eligibility

What is being tested?

The study tests whether Oxandrolone can aid healing post-multiligament knee surgery compared to a placebo. Participants will receive either the medication or placebo for 12 weeks to assess effectiveness in recovery and muscle mass restoration.See study design

What are the potential side effects?

Oxandrolone may cause side effects similar to other anabolic steroids such as liver issues, hormonal changes, mood swings, increased risk of heart disease, and changes in cholesterol levels.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ change from baseline at 52 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~change from baseline at 52 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline at 52 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

body fat percentage

lean body mass

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Treatment groupExperimental Treatment1 Intervention

Oxandrolone

Group II: Placebo GroupPlacebo Group1 Intervention

Placebo

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Oxandrolone

2004

Completed Phase 1

~60

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

George F. HatchLead Sponsor

George Hatch, MDPrincipal InvestigatorUniversity of Southern California

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does the Treatment group possess the endorsement of the FDA?

"Based on the Phase 4 status of this treatment, our team at Power assigned a safety rating of 3."

Answered by AI

To what number has enrollment in this clinical experiment reached?

"Affirmative. The information found on clinicaltrials.gov indicates that this trial is actively enrolling patients, with the initial post dating back to July 1st 2023 and a recent update occurring November 17th 2023. Sixty participants must be recruited from one site for this study to reach completion."

Answered by AI

Are there any open opportunities to be part of this experiment?

"Confirmed. Data on clinicaltrials.gov conveys that this investigation is actively searching for participants, which was posted initially on July 1st 2023 and most recently updated November 17th 2023. The study requires 60 people to be recruited from a single testing site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Oxandrolone Multiligament Knee

George F. Hatch 2023. "Oxandrolone Multiligament Knee". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05893069.