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Corticosteroid

Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution) for Labor Pain

Phase 4

Waitlist Available

Research Sponsored by Henry Ford Health System

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 72 hours after initial administration of labor epidural

Awards & highlights

Study Summary

This trial is testing how much epidurals slow down the progress of labor by measuring the strength of abdominal contractions before and after receiving the epidural.

Eligible Conditions

Labor Pain
Pain relief
Maternal Procedure

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 72 hours after initial administration of labor epidural

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 72 hours after initial administration of labor epidural

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 72 hours after initial administration of labor epidural for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

The change in intraabdominal pressure (surrogate of maternal force)

Secondary outcome measures

Apgar scores

Duration of second stage of labor

Mode of delivery

Trial Design

1Treatment groups

Experimental Treatment

Group I: Epidural AnalgesiaExperimental Treatment1 Intervention

All subjects will be given epidural analgesia to treat their labor pain. As part of standard protocol for all patients who receive a labor epidural, the epidural will then be tested using 3ml of 1.5% lidocaine and 1:200,000 epinephrine test solution, and the epidural catheter will then be loaded with 10ml of 0.125% bupivacaine solution. The epidural catheter will then be connected to a programmed intermittent epidural bolus pump which will administer 5ml of a 0.125% bupivacaine/2mcg fentanyl solution every 30minutes. The first dose will be given following 30minutes after the loading dose. 30 minutes after loading the loading dose and after the first pump dose has been given, we will assess the VAS pain scores and the level of the analgesic based on decreased sensation to ice.

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Who is running the clinical trial?

Henry Ford Health SystemLead Sponsor

300 Previous Clinical Trials

2,099,999 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What potential hazards might accompany the use of a 0.125% bupivacaine/2mcg fentanyl solution for Epidural analgesia?

"Clinical data suggests that epidural analgesia is a safe option, thus it received a 3 on our risk scale. This Phase 4 trial indicates the intervention has been approved for use."

Answered by AI

What sort of pain can be alleviated by the administration of Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution)?

"Permphigus is typically managed with Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution). This treatment can also be efficacious in tackling acute nonspecific tenosynovitis, general anesthesia and lupus erythematosus cell."

Answered by AI

Are there any documented cases regarding the utilization of a combination of bupivacaine and fentanyl for epidural analgesia?

"Currently, 141 clinical trials involving Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution) have been launched of which 26 are in the Phase 3 stage. Predominantly located in Germantown, Tennessee, these studies span a total of 204 sites across the country."

Answered by AI

Is this investigation currently open to participants?

"Affirmative. According to clinicaltrials.gov, this study is actively searching for 34 participants from one medical site and was initially posted on November 2nd 2020 with the most recent update being made 8th March 2022."

Answered by AI

What is the cumulative enrollment for this research trial?

"Indeed, the information on clinicaltrials.gov verifies that this trial is open to patients and actively recruiting. It was initially posted in November of 2020 with its last update taking place on March 8th 2022; 34 individuals are sought from a solitary medical site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effect of Epidural Analgesia During Labor on Force of Maternal Push

Katherine Nowak 2020. "Effect of Epidural Analgesia During Labor on Force of Maternal Push". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04888858.