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Coil

coiling for Brain Aneurysm (STAT Trial)

N/A

Waitlist Available

Led By Jean Raymond, MD

Research Sponsored by Centre hospitalier de l'Université de Montréal (CHUM)

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 months

Awards & highlights

STAT Trial Summary

This trial is testing whether adding a stent to the treatment of an aneurysm reduces the rate of recurrence.

Eligible Conditions

Brain Aneurysm

STAT Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Recurrence rate of target aneurysm

Secondary outcome measures

Incidence of in-stent stenosis defined as the number of subjects with a reduction in the luminal diameter of greater than 50%

Overall morbidity and mortality given by the modified Rankin Score

Rate of Procedural complications defined as number of subjects with reported peri-procedural Adverse Events

+1 more

STAT Trial Design

2Treatment groups

Active Control

Group I: coilingActive Control1 Intervention

endovascular coiling with any type of currently approved coil (first or second generation)

Group II: coiling plus stentingActive Control2 Interventions

endovascular stenting with or without coiling. The stent may be any of the currently approved stents for intracranial aneurysms.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University Hospital, BrestOTHER

516 Previous Clinical Trials

239,187 Total Patients Enrolled

Centre hospitalier de l'Université de Montréal (CHUM)Lead Sponsor

366 Previous Clinical Trials

129,432 Total Patients Enrolled

Jean Raymond, MDPrincipal InvestigatorCentre Hospitalier de l'Université de Montréal - Hôpital Notre Dame

9 Previous Clinical Trials

4,110 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What adverse effects could be experienced from the practice of coiling?

"Coiling is deemed safe, as evidenced by its Phase 4 trial status and the subsequent score of 3."

Answered by AI

How many geographic sites are currently conducting this trial?

"Centre Hospitalier de l'Université de Montréal - Hôpital Notre Dame, University of Alberta Hospital, Queen Elizabeth II Health Sciences Centre and 4 other medical sites are participating in this trial. These locations can be found in Montreal (Quebec), Edmonton (Alberta) and Halifax (Nova Scotia)."

Answered by AI

How many participants are being monitored in the course of this medical research?

"This clinical trial needs to enroll 600 suitable participants from various locations, including Centre Hospitalier de l'Université de Montréal - Hôpital Notre Dame in Montreal and University of Alberta Hospital in Edmonton."

Answered by AI

Are any new patients being accepted for this medical trial?

"This clinical trial is open for enrolment, as reported on the directory hosted by clinicaltrials.gov. The first posting date was August 25th 2011 and it was last updated June 7th 2022."

Answered by AI

Recent research and studies

Journal of NeuroInterventional SurgeryJournal

The Design of the Stenting in Aneurysm Treatments (STAT) Trial

Darsaut, Tim E, Jean Raymond, and for the STAT Collaborative Group. 2011. “The Design of the Stenting in Aneurysm Treatments (STAT) Trial”. Journal of Neurointerventional Surgery. BMJ. doi:10.1136/neurintsurg-2011-010065.

The Lancet NeurologyJournal

Unruptured Intracranial Aneurysms: Why We Must Not Perpetuate the Impasse for Another 25 Years

Naggara, Olivier, Tim Darsaut, Denis Trystram, Lambros Tselikas, and Jean Raymond. 2014. “Unruptured Intracranial Aneurysms: Why We Must Not Perpetuate the Impasse for Another 25 Years”. The Lancet Neurology. Elsevier BV. doi:10.1016/s1474-4422(14)70091-2.

clinicaltrials.govStudy

Stenting in the Treatment of Aneurysm Trial

2011. "Stenting in the Treatment of Aneurysm Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01340612.