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Virus Therapy

Flu Vaccine SD for Elderly Immune System

Phase 4
Waitlist Available
Led By Janet E McElhaney, MD
Research Sponsored by Health Sciences North Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up five years
Awards & highlights

Study Summary

This 5-year proposal is a randomized study of split-virus influenza vaccine (SVV) in a high-dose (HD) vs. standard-dose (SD) formulation in each of five influenza seasons to define the key determinants of vaccine-mediated protection against influenza and how these immunologic mediators may be enhanced by vaccination with a newly approved high-dose influenza vaccine in older people

Eligible Conditions
  • Elderly Immune System

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~five years
This trial's timeline: 3 weeks for screening, Varies for treatment, and five years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of Influenza Cases

Trial Design

2Treatment groups
Active Control
Group I: Flu Vaccine SDActive Control1 Intervention
Fluzone Standard Dose Influenza Vaccine
Group II: Flu Vaccine HDActive Control1 Intervention
Fluzone High Dose Influenza Vaccine

Find a Location

Who is running the clinical trial?

Health Sciences North Research InstituteLead Sponsor
10 Previous Clinical Trials
2,009 Total Patients Enrolled
UConn HealthOTHER
211 Previous Clinical Trials
60,536 Total Patients Enrolled
Janet E McElhaney, MDPrincipal InvestigatorHealth Sciences North Research Institute

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Immune Response to High-Dose vs. Standard Dose Influenza Vaccine
Janet McElhaney 2014. "Immune Response to High-Dose vs. Standard Dose Influenza Vaccine". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02297542.
All > Flu
~8 spots leftby Apr 2025
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