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Antibiotic

Oral Vancomycin for Clostridium Difficile Infection

Phase 4
Waitlist Available
Led By Mindy Sampson, DO
Research Sponsored by University of South Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 90 days
Awards & highlights

Study Summary

This trial is testing whether vancomycin can prevent Clostridium difficile infections.

Eligible Conditions
  • Clostridium Difficile (C. diff) Infection
  • Clostridium Difficile Infection

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~90 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 90 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Recurrence Rate
Secondary outcome measures
Risk factors associated clostridium difficile infection recurrences

Side effects data

From 2021 Phase 4 trial • 15 Patients • NCT03388268
25%
Abdominal pain
13%
Syncope, altered mental status
13%
Volume overload
13%
Hypoxemia
100%
80%
60%
40%
20%
0%
Study treatment Arm
Placebo
Oral Vancomycin

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Study drugExperimental Treatment1 Intervention
Oral vancomycin 125mg twice a day prescribed for the duration of antibiotics
Group II: PlaceboPlacebo Group1 Intervention
Matched placebo twice a day prescribed for the duration of antibiotics
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Oral Vancomycin
2017
Completed Phase 4
~200

Find a Location

Who is running the clinical trial?

University of South FloridaLead Sponsor
407 Previous Clinical Trials
186,783 Total Patients Enrolled
Mindy Sampson, DOPrincipal InvestigatorUniversity of South Florida

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any vacancies open to participants in this investigation?

"Confirmed, the details hosted on clinicaltrials.gov indicate that this medical trial is actively recruiting participants. It was first posted on September 1st 2019 and most recently updated November 5th 2021 with a requirement of 130 patients from two healthcare centres."

Answered by AI

Has Oral Vancomycin been validated by the Food and Drug Administration?

"With Phase 4 clinical trials already completed, the safety of Oral Vancomycin receives a rating of 3."

Answered by AI

How is Oral Vancomycin commonly employed to address medical conditions?

"Oral Vancomycin can be used to address staphylococcal infections, contagions from staphylococci bacteria, and enterocolitis caused by Staphelycoccus aureus."

Answered by AI

What other research projects have been conducted with Oral Vancomycin as a focus?

"At this moment in time, 55 clinical trials are being conducted to study oral vancomycin. 6 of those investigations have reached Phase 3, and 315 sites across the globe are hosting experiments for potential efficacy. The majority of studies related to Oral Vancomycin take place in Jupiter Florida."

Answered by AI

What is the scope of individuals being treated through this research?

"Indeed, as per the records on clinicaltrials.gov, this research project is now recruiting patients for participation. It was first announced in September 2019 and recently updated on November 5th 2021; 130 participants are being sought at two sites of care."

Answered by AI

Who else is applying?

What state do they live in?
New York
Texas
How old are they?
18 - 65
What site did they apply to?
Infectious Disease Associates of Tampa Bay
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
Recent research and studies
clinicaltrials.govStudy
Oral Vancomycin for Secondary Prophylaxis of Clostridium Difficile Infection (CDI)
2019. "Oral Vancomycin for Secondary Prophylaxis of Clostridium Difficile Infection (CDI)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04000555.
~5 spots leftby Apr 2025
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